Sr. Research Scientist, In Vitro DMB

Scorpion Therapeutics; Wilmington (DE); On-site; USD 120,000 - 160,000; Full time

Job summary

Scorpion Therapeutics in Wilmington, DE seeks a Senior Research Scientist specializing in high-throughput drug metabolism and ADME assays to support assay development, data analysis, and lab operations.

The role involves designing LC-MS/MS methods, increasing automation, troubleshooting instruments, and collaborating with cross-functional teams to ensure rapid data processing and compliant reporting.

Qualifications

• PhD with 3+ years or Bachelor with 10+ years in a relevant scientific field.
• Extensive HT drug metabolism/ADME experience, preferably with RapidFire or Echo.
• Skilled in liquid handling robotics and LC-MS/MS bioanalysis.
• Strong attention to detail and independent task management.

Responsibilities

• Design and optimize LC-MS/MS methods.
• Miniaturize robotics workflows with high-throughput automation.
• Troubleshoot instruments and maintain equipment.
• Manage data reporting and archiving.
• Collaborate with cross-functional teams and lab staff.
• Perform routine lab tasks.

Skills

HTLC-MS/MS

Liquid handling robots

Data analysis

Independent task mgmt

Education

PhD in relevant field

Bachelor's in relevant field

Tools

Agilent RapidFire

Sciex Echo

Hamilton robots

Tecan automation

Job description

Role

Senior Research Scientist specializing in high-throughput drug metabolism and ADME assays, supporting assay development, data analysis, and laboratory operations.

Responsibilities

• design and optimize LC-MS/MS methods


• miniaturize robotics workflows with high-throughput automation


• troubleshoot instruments


• manage data reporting and archiving


• Collaborate with cross-functional teams and laboratory staff


• perform routine lab tasks


• maintain equipment

Requirements

• Ph.D. with 3+ years or Bachelor's with 10+ years in a relevant scientific field


• extensive experience in high-throughput drug metabolism/ADME, preferably using Agilent Rapid Fire or Sciex Echo platforms


• Skilled in liquid handling robotics (Hamilton, Tecan) and LC-MS/MS bioanalysis


• Strong attention to detail, independent task management, and effective communication are essential

High-Value

focus on biochemical assays supporting drug discovery, ADME profiling, high-throughput LC-MS/MS, robotics automation, and rapid data processing.

No specific therapeutic area or development stage specified.

Work setup: not explicitly stated.