Bench Scientist 42792

Makro Scientific; Groton (CT); On-site; USD 70,000 - 90,000; Full time

Job summary

Makro Scientific in Groton, Connecticut, is seeking a scientist to conduct in vitro drug metabolism studies and support R&D portfolios. The ideal candidate will perform standard chemical calculations, work with biohazardous material, and analyze data using LC/MS and other software.

Additionally, effective communication and adherence to laboratory SOPs are essential. Candidates must have a BS in chemistry or related field and 3-6 years of experience. Experience with assay development and automation is preferable.

Qualifications

• 3-6 years of relevant experience in drug metabolism studies.
• Ability to effectively communicate both verbally and in writing.
• Solid training in chemical calculations for lab solutions preparation.

Responsibilities

• Conduct in vitro drug metabolism studies.
• Prepare laboratory solutions and dilutions.
• Quantify samples by LC/MS and analyze data.

Skills

Chemical calculations

Data analysis using Excel/Graph Pad Prism

Laboratory SOP adherence

Effective communication skills

Education

BS in chemistry, biochemistry, biology or related field

Tools

LC-MS

Microsoft Office

Job description

Job Description

The scientist will work closely with his/her supervisor to conduct routine in vitro drug metabolism studies designed to evaluate molecules as inhibitors of drug metabolizing enzyme. The individual will work in the Pharmacokinetics, Dynamics and Metabolism (PDM) department to support R&D portfolios. Perform standard chemical calculations to accurately prepare laboratory solutions and dilutions for screening. Conduct in vitro experiments with bio hazardous material both manually and with robotic systems. Quantification of samples by LC/MS and analyzing data using excel and/or Graph Pad Prism. Generate high quality data in a timely manner, reviewing and uploading data into databases. With support of his/her supervisor and colleagues, the candidate will work as a member of a team and be accountable for the critical appraisal of their results. Accurate record keeping and ability to follow precise steps in a protocol are required. Perform and maintain lab supply inventory and order as appropriate.

Qualifications

• BS in chemistry, biochemistry, biology or related field.
• Experience: 3-6 years.

Additional Information

• Must possess effective verbal and written communication skills.
• Ability to perform and record data entry via computer systems while adhering to laboratory SOPs is mandatory.
• Previous knowledge of Universal Precautions, Blood Borne Pathogen training, Microsoft Office including Excel and Graph Pad Prism is preferable.
• Candidate must be able to quickly learn new in-house software for data management.
• Candidate will have solid training and knowledge in standard chemical calculations to accurately prepare laboratory solutions and calculate dilutions for screening.
• Experience in assay development and mechanisms of enzyme inhibition are preferred.
• Experience with automation of assays and LC-MS is also desired.