Senior Upstream Process Scientist - Scale-Up & Tech Transfer

Pfizer Inc; Bothell (WA); On-site; USD 69,000 - 114,000; Full time

Benefits offered by this job

Relocation assistance may be available

Comprehensive benefits package

On-site work environment

Job summary

Pfizer is seeking a Senior Associate Scientist (R2) in Upstream Process Development to develop robust, scalable manufacturing processes for recombinant proteins for clinical trials. The role involves bench-scale experiments, scale-down models, and collaboration with pilot and GMP facilities.

Responsibilities include technology transfer, data documentation in ELNs, supporting regulatory submissions, and working in a collaborative team with occasional weekend work.

Qualifications

• Bachelor's degree with 3 years' industrial experience or Master's degree with 0-2 years experience in Chemical / Biochemical Engineering, Cell Biology, Biotechnology, Biomedical Engineering or a relevant field.
• Relevant research experience in a laboratory setting is required.
• Ability to grasp scientific concepts, interpret complex data, and formulate new hypothesis.
• Competency in aseptic laboratory technique and the ability to design and carry out complex experiments and interpret data.
• Demonstrated effectiveness in collaborative projects, and ability to communicate effectively with scientists and management in a highly matrixed organization.

Responsibilities

• Design and execute experiments in appropriate scale-down models such as shake flasks and bioreactors in an effort to develop robust, high yield, and scalable manufacturing processes
• Serve as upstream technical lead; ensure accurate technology transfer to pilot and GMP manufacturing facilities; provide technical support during manufacturing campaign as needed
• Timely and accurately document data in electronic lab notebooks; author technical reports and contribute to relevant sections of regulatory submissions such as IND and BLA
• Participate and contribute to discussions in lab and project team meetings on design of experiments and interpretation of data
• Contribute to safe, efficient, and harmonious lab environment; strong lab citizen and collaborative team player
• Occasionally work over the weekend to passage flasks, sample bioreactors or perform other essential tasks

Skills

Scientific analysis

Aseptic technique

Collaborative teamwork

Communication

Data interpretation

Python programming

Education

Bachelor's degree in Chemical/Biochemical Engineering, Cell Biology, Biotechnology, Biomedical Engineering or related field

Master's degree in related field

Tools

Ambr15

Ambr250

Python

Job description

Pfizer is seeking a Senior Associate Scientist (R2) in Upstream Process Development to develop robust, scalable manufacturing processes for recombinant proteins for clinical trials. The role involves bench-scale experiments, scale-down models, and collaboration with pilot and GMP facilities.

Responsibilities include technology transfer, data documentation in ELNs, supporting regulatory submissions, and working in a collaborative team with occasional weekend work.