Senior Downstream Scientist: Bioprocess Innovation

Pfizer; Bothell (WA); In loco; USD 94.000 - 156.000; Tempo pieno

Descrizione del lavoro

Pfizer is seeking a Senior Scientist (R4) for the Downstream Process Development group in Bioprocess R&D. The role emphasizes hands-on laboratory work to develop and optimize recovery and purification processes for recombinant proteins in mammalian cell culture, supporting clinical programs.

The candidate will collaborate across sites, drive scalable downstream strategies, and contribute to technology transfer, process characterization, and regulatory filings.

Competenze

• Hands-on experience in recombinant protein downstream process development.
• Strong understanding of protein chemistry and protein analytics.
• Proven ability to independently drive experimental work and deliver results.
• Experience using AI tools for problem solving and productivity.

Mansioni

• Design and execute small-scale downstream process development studies, with support for pilot-scale and manufacturing purification activities.
• Analyze experimental data to develop, test, and refine hypotheses that improve the fundamental understanding of recovery and purification processes.
• Contribute to process characterization, validation strategies, Quality by Design (QbD) approaches, and regulatory filings.
• Author internally reviewed technical reports, present scientific results to cross-functional teams and management, and publish externally as appropriate.
• Identify and implement opportunities for operational efficiency and continuous improvement across Bioprocess R&D workflows.
• Support change initiatives related to business infrastructure, platforms, and technologies to enable pipeline, legacy, and innovation programs.

Conoscenze

Bioprocessing

Data analysis

QbD

Regulatory filings

AI tools

Team collaboration

Formazione

Bachelor's degree with 8+ years of relevant experience

Master's degree with 6+ years of relevant experience

PhD with 0-3 years of experience

Strumenti

Data acquisition systems

Process control systems

Statistical design

ChatGPT / Copilot

Descrizione del lavoro

Pfizer is seeking a Senior Scientist (R4) for the Downstream Process Development group in Bioprocess R&D. The role emphasizes hands-on laboratory work to develop and optimize recovery and purification processes for recombinant proteins in mammalian cell culture, supporting clinical programs.

The candidate will collaborate across sites, drive scalable downstream strategies, and contribute to technology transfer, process characterization, and regulatory filings.