Senior Upstream Process Scientist — Bioprocess R&D Lead

Pfizer Inc.; Bothell (WA); In loco; USD 69.000 - 114.000; Tempo pieno

Descrizione del lavoro

Pfizer Inc. is seeking a Senior Associate Scientist (R2) in the Upstream Process Development group to design and optimize manufacturing processes for recombinant proteins and other modalities for early- and late-phase clinical trials.

You will work with bench-top bioreactors, scale-down models, and cross-functional teams to develop robust, scalable processes. You will lead upstream activities, transfer technology to pilot and GMP facilities, and contribute to regulatory submissions while

Competenze

• Bachelor’s degree with 3 years’ industrial experience or Master’s with 0–2 years in Chemical/Biochemical Engineering, Cell Biology, Biotechnology, Biomedical Engineering or related field.
• Relevant research experience in a laboratory setting is required.
• Ability to grasp scientific concepts, interpret complex data, and formulate new hypotheses.

Mansioni

• Design and execute experiments in scale-down models (shake flasks, bioreactors) to develop robust, high-yield, scalable manufacturing processes.
• Serve as upstream technical lead; ensure accurate technology transfer to pilot and GMP facilities; provide technical support during manufacturing campaigns.
• Document data in electronic lab notebooks; author technical reports and contribute to regulatory submissions (IND, BLA).
• Participate in lab and project team discussions on DOE design of experiments and data interpretation.
• Contribute to a safe, efficient lab environment and be a collaborative team player.
• Occasionally work weekends to passage flasks, sample bioreactors, or perform essential tasks.

Conoscenze

Scientific data interpretation

Aseptic technique

Collaboration & communication

Hypothesis formulation

Formazione

Bachelor’s with 3+ years or Master’s with 0–2 years in Chemical/Biochemical Eng, Cell Biology, Biotechnology, Biomedical Engineering or related field

Strumenti

Ambr platforms

Bioreactor operations

Process modeling

Multivariate data analysis

Python programming

Descrizione del lavoro

Pfizer Inc. is seeking a Senior Associate Scientist (R2) in the Upstream Process Development group to design and optimize manufacturing processes for recombinant proteins and other modalities for early- and late-phase clinical trials.

You will work with bench-top bioreactors, scale-down models, and cross-functional teams to develop robust, scalable processes. You will lead upstream activities, transfer technology to pilot and GMP facilities, and contribute to regulatory submissions while