Senior Scientist, Targeted LNP Delivery & AI-Driven Formulations

RXinsider LTD.; Cambridge (MA); On-site; USD 131,000 - 209,000; Full time

Benefits offered by this job

Competitive healthcare

Well-being resources

Family planning benefits

Generous paid time off

Savings and investments

Location-specific perks

Job summary

Moderna in Cambridge, MA is seeking an accomplished Scientist to lead the development of targeted lipid nanoparticle formulations within a fast-paced R&D organization. You will advance LNP self-assembly, engineer delivery systems for small- and large-molecule payloads beyond the liver, and integrate high-throughput formulation, automation, and AI/ML approaches to accelerate discovery.

This site-based role requires deep expertise in LNP design and strong leadership to mentor researchers and

Qualifications

• Ph.D. in a related discipline with 2+ years of experience.
• Deep expertise in LNP design, formulation, and physicochemical characterization.
• Experience advancing targeted or extra-hepatic delivery platforms preferred.
• Experience with high-throughput workflows, automation, and AI/ML data analysis.
• Proven leadership mentoring scientists in a fast-paced setting.

Responsibilities

• Drive research programs on targeted, extra-hepatic LNP delivery—from hypothesis generation through in-vivo evaluation
• Develop and optimize LNP self-assembly processes; refine composition, payload loading, and surface modifications for tissue and cell-type specificity
• Advance LNP formulation discovery by leveraging high-throughput formulation, automation, and AI/ML-enabled data analysis to accelerate innovation, optimize formulations, and drive data-informed decision-making across multidisciplinary teams
• Independently Design and execute experiments; analyze, interpret, and clearly communicate data to multidisciplinary project teams and leadership
• Implement and innovate advanced physicochemical and biophysical characterization methods to elucidate structure-function relationships
• Maintain rigorous electronic laboratory notebooks, SOPs, and study documentation consistent with company expectations
• Provide scientific leadership and mentorship to research associates while partnering with cross-functional teams and external collaborators to prioritize activities, solve technical challenges, and ensure the timely achievement of project objectives and key milestones.

Job description

Moderna in Cambridge, MA is seeking an accomplished Scientist to lead the development of targeted lipid nanoparticle formulations within a fast-paced R&D organization. You will advance LNP self-assembly, engineer delivery systems for small- and large-molecule payloads beyond the liver, and integrate high-throughput formulation, automation, and AI/ML approaches to accelerate discovery.

This site-based role requires deep expertise in LNP design and strong leadership to mentor researchers and