Senior Scientist, Targeted LNP Delivery & AI-Driven Formulation

Tribonet; Northern (KY); Hybrid; USD 131,000 - 209,000; Full time

Benefits offered by this job

Healthcare benefits

Well-being programs

Parental benefits

Paid time off

Investment options

Job summary

Moderna seeks a Scientist to lead targeted lipid nanoparticle (LNP) formulation programs in a fast-paced R&D setting. You will drive LNP self-assembly, engineer delivery systems for small- and large-molecule payloads beyond the liver, and harness AI/ML to accelerate discovery.

This site-based role requires mentorship of researchers, hands-on experimental design, and collaboration across cross-functional teams to meet project milestones using advanced analytical methods.

Qualifications

• Ph.D. in related field with 2+ years of experience.
• Deep expertise in lipid nanoparticle design, formulation, and physicochemical characterization; extra-hepatic delivery preferred.
• Experience implementing high-throughput formulation workflows, automation, and AI/ML-enabled data analysis.
• Proven leadership mentoring scientists and cross-functional collaboration in fast-paced environments.
• Proficiency with analytical techniques for nanoparticle size, morphology, composition, and stability.

Responsibilities

• Lead research programs on targeted, extra-hepatic LNP delivery from hypothesis to in-vivo evaluation.
• Develop and optimize LNP self-assembly and surface modifications for tissue specificity.
• Advance formulation discovery using high-throughput methods, automation, and AI/ML data analysis.
• Independently design and execute experiments; communicate data to teams and leadership.
• Apply advanced physicochemical and biophysical methods to elucidate structure–function relationships.
• Maintain rigorous electronic notebooks and SOPs per company standards.
• Mentor research associates and partner with cross-functional teams to achieve milestones.

Skills

LNP design

High-throughput formulation

Lab automation

AI/ML data analysis

Leadership mentoring

Nanoparticle analysis

Education

Ph.D. in Pharmaceutical Sciences, Chemistry, Chemical Engineering, Materials Science, or related

Tools

DLS

CryoEM

SAXS

ITC

NMR

nFCM

Job description

Moderna seeks a Scientist to lead targeted lipid nanoparticle (LNP) formulation programs in a fast-paced R&D setting. You will drive LNP self-assembly, engineer delivery systems for small- and large-molecule payloads beyond the liver, and harness AI/ML to accelerate discovery.

This site-based role requires mentorship of researchers, hands-on experimental design, and collaboration across cross-functional teams to meet project milestones using advanced analytical methods.