Senior Proteomics Scientist - High-Throughput Mass Spec

Amgen SA

Thousand Oaks, Northern (CA, KY)

Hybrid

USD 110,000 - 170,000

Full time

9 days ago
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Benefits offered by this job

Comprehensive benefits
Discretionary annual bonus
Stock-based incentives
Generous time-off
Flexible work models

Job summary

Amgen is seeking a Scientist or Senior Scientist in mass spectrometry–based proteomics to join Thousand Oaks, CA. You will generate proteomic insights that support target identification, drug discovery, and screening technology advancement.

You will develop high‑throughput workflows, automate sample prep, LC–MS/MS analyses, and collaborate with biology and chemistry teams to drive data‑driven decisions. Strong hands‑on expertise with Orbitrap platforms and a focus on reproducible results are

Qualifications

  • Doctorate degree with relevant experience or equivalent.
  • Bachelor’s with 4+ years of related experience or Master’s with 2+ years of related experience.

Responsibilities

  • Design, develop, optimize, and implement high‑throughput mass spectrometry–based proteomics workflows and screening platforms to accelerate drug discovery.
  • Execute automated sample preparation and LC–MS/MS analyses across a broad range of high‑throughput proteomics assays.
  • Collaborate with therapeutic area, biology and chemistry teams as a technical expert to support data‑driven decisions.
  • Analyze and interpret proteomics data to generate insights on mechanism of action and target engagement.
  • Operate, maintain, and improve high‑throughput MS systems and workflows.
  • Present findings at meetings and communicate plans, results, and analyses to cross‑functional teams.
  • Maintain accurate documentation of experiments and data analyses.

Skills

Mass spectrometry
High-throughput workflows
Data analysis

Education

PhD/PharmD/MD
Master's + 2 yrs
Bachelor's + 4 yrs

Tools

Orbitrap‑based MS
LC–MS/MS

Job description

Amgen is seeking a Scientist or Senior Scientist in mass spectrometry–based proteomics to join Thousand Oaks, CA. You will generate proteomic insights that support target identification, drug discovery, and screening technology advancement.

You will develop high‑throughput workflows, automate sample prep, LC–MS/MS analyses, and collaborate with biology and chemistry teams to drive data‑driven decisions. Strong hands‑on expertise with Orbitrap platforms and a focus on reproducible results are

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