Senior Manager, CAR-T Cell Manufacturing (Liso-cel)

Bristol-Myers Squibb Co; Summit (NJ); On-site; USD 119,000 - 144,000; Full time

Benefits offered by this job

Comprehensive benefits

Flexible Time Off

Wellbeing support

Career development

Job summary

Bristol Myers Squibb is seeking a Senior Manager of Manufacturing to lead Cell Therapy operations on a 24/7 schedule, overseeing Manufacturing Managers and Work Centered Teams at our Summit, NJ site. The role emphasizes safety, compliance, and continuous improvement, reporting to the Associate Director.

The position requires extensive cGMP knowledge, process expertise in CAR-T manufacturing, and a proven record of leading high-performing teams.

Qualifications

• Bachelor’s degree in a related field, or equivalent work experience; advanced degree preferred.
• 7+ years of manufacturing experience, including at least 5 years of leadership experience managing direct reports.

Responsibilities

• Ensure Manufacturing Managers and WCT members execute Cell Therapy manufacturing in compliance with cGMPs, approved SOPs, WIs, batch records, safety expectations, and ALCOA+ documentation principles.
• Maintain hands-on process expertise across unit operations, support MRB data collection, provide weekend/technical coverage as needed, and develop CAR-T manufacturing and regulatory knowledge.
• Manage production resources by tracking availability, supporting scheduling needs, maintaining records of planned/unplanned absences, and hiring talent aligned with job requirements, budget, and BMS values.
• Set priorities, establish WCT goals, monitor performance, and report metrics and progress through Tier meetings, performance reviews, site control plans, and cross-functional manufacturing forums.
• Maintain 100% on-time training compliance, ensure personnel are qualified before performing tasks, allocate time for training, and disqualify personnel from GMP tasks when compliance gaps are observed.
• Build and develop high-performing teams through recruiting, onboarding, Workday profile maintenance, performance management, recognition, coaching, regular 1:1s, career development, and timely feedback.
• Lead deviation troubleshooting and quality record ownership as BPO/BTA, ensure clear and timely deviation entries, monitor metrics, identify repeat causes, drive on-time closure, and prevent recurrence through continuous improvement.
• Participate in CAPAs, Change Controls, and projects; define or own actions for Manufacturing and ensure implementation before due dates.
• Control expenses within area of influence, including overtime, supplies, and travel/expense costs.
• Model leader behaviors by maintaining shopfloor presence, conducting Gemba/Go & See activities, using tiered management, visual management, coaching kata, root-cause problem solving, risk escalation, and cross-functional collaboration.

Skills

Leadership

cGMP

EHS

Biotech manufacturing

Lean manufacturing

Green Belt

Education

Bachelor's degree in related field

Advanced degree preferred

Job description

Bristol Myers Squibb is seeking a Senior Manager of Manufacturing to lead Cell Therapy operations on a 24/7 schedule, overseeing Manufacturing Managers and Work Centered Teams at our Summit, NJ site. The role emphasizes safety, compliance, and continuous improvement, reporting to the Associate Director.

The position requires extensive cGMP knowledge, process expertise in CAR-T manufacturing, and a proven record of leading high-performing teams.