CAR-T Manufacturing Ops Manager – Night Shift (Liso-cel)

Bristol-Myers Squibb Co; Summit (NJ); On-site; USD 104,000 - 125,000; Full time

Job summary

Bristol Myers Squibb is seeking a Manager, CAR-T Manufacturing Operations in Summit, NJ, to lead compliant, safe, and reliable commercial CAR-T manufacturing activities in an aseptic cGMP environment. This role provides direct leadership to manufacturing personnel and partners with Quality, Supply Chain, and other stakeholders to ensure production continuity and continuous improvement.

The candidate will drive safety culture, ensure adherence to SOPs and batch records, and manage staffing,

Qualifications

• Bachelor’s degree in life sciences, engineering, biotechnology, or a related discipline.
• Experience in regulated cGMP manufacturing environment, preferably in biologics, cell therapy, aseptic processing, or pharmaceutical manufacturing.
• Experience leading CAR-T or cell therapy manufacturing operations is preferred.

Responsibilities

• Ensure compliant execution of commercial CAR-T manufacturing operations in accordance with cGMP requirements, approved SOPs, work instructions, batch records, and quality standards.
• Maintain hands-on manufacturing expertise and provide technical guidance, training, coaching, and real-time operational support to ensure successful product execution and schedule adherence.
• Gain and maintain full process qualification, supporting manufacturing activities to ensure operational flexibility, team capability, and production continuity.
• Drive a strong safety culture through leadership presence, shopfloor engagement, risk identification, hazard mitigation, and adherence to workplace safety practices.
• Oversee batch record review, manufacturing documentation, and data integrity compliance, ensuring adherence to ALCOA+ principles and right-first-time performance.
• Manage workforce planning, staffing, scheduling, hiring, onboarding, performance management, training compliance, and employee development to ensure operational readiness.
• Monitor and communicate operational performance through KPIs, production metrics, tier meetings, performance reviews, and resource planning activities.

Skills

cGMP

Leadership

People management

Gemba

Deviation management

Continuous improvement

Education

Bachelor’s degree in life sciences/engineering/biotechnology

Job description

Bristol Myers Squibb is seeking a Manager, CAR-T Manufacturing Operations in Summit, NJ, to lead compliant, safe, and reliable commercial CAR-T manufacturing activities in an aseptic cGMP environment. This role provides direct leadership to manufacturing personnel and partners with Quality, Supply Chain, and other stakeholders to ensure production continuity and continuous improvement.

The candidate will drive safety culture, ensure adherence to SOPs and batch records, and manage staffing,