Senior Director, LNP Formulation & Process Development

Flagship Pioneering, Inc.; Cambridge (MA); On-site; USD 213,000 - 281,000; Full time

Benefits offered by this job

Healthcare coverage

Annual incentive program

Retirement benefits

A broad range of other benefits

Job summary

Mirai Bio in Cambridge, MA seeks a Senior Director of Lipid Nanoparticle (LNP) Formulation & Process Development to lead the LNP formulation, process development, and small-scale production supporting partner and internal programs.

This role provides scientific and operational leadership across programs, builds scalable capabilities, mentors a team, interfaces with clients, and collaborates with Analytical Development, Translational Biology, Project Management, and other functions to advance

Qualifications

• Ph.D./M.S./B.S. with extensive industry experience in LNP formulation and process development.
• Demonstrated ability to lead complex technical programs and multi-project portfolios.
• Strong leadership and client-facing communication skills.

Responsibilities

• Lead LNP formulation, process development, and small-scale production supporting partner and internal programs.
• Establish technical strategy and best practices for LNP formulation, process development, characterization, and production across payloads and applications.
• Provide senior technical leadership across programs including development strategy, experimental planning, data review, risk mitigation, and recommendations.
• Serve as a senior technical interface with clients and partners supporting proposals, project scopes, and BD activities.
• Oversee non-GMP production of LNP formulations for in vitro, in vivo, and preclinical studies.
• Drive troubleshooting, process optimization, tech transfer, and continuous improvement of LNP production for mRNA, siRNA, gene-editing components, and other nucleic acid payloads.
• Establish workflows and documentation to improve quality, reproducibility, efficiency, and scalability.
• Lead and develop the LNP team and manage priorities, resources, and growth.
• Collaborate cross-functionally to align LNP development with broader program and company objectives.

Skills

LNP formulation

Process development

Program leadership

Client-facing

Team management

CMO/CDMO experience

Education

Ph.D. in Pharmaceutical Sciences

M.S. in a related field

B.S. in a related field

Job description

Mirai Bio in Cambridge, MA seeks a Senior Director of Lipid Nanoparticle (LNP) Formulation & Process Development to lead the LNP formulation, process development, and small-scale production supporting partner and internal programs.

This role provides scientific and operational leadership across programs, builds scalable capabilities, mentors a team, interfaces with clients, and collaborates with Analytical Development, Translational Biology, Project Management, and other functions to advance