Protein Purification Scientist II — Onsite in Carlsbad

TekWissen LLC; Carlsbad (CA); On-site; USD 39,000 - 48,000; Full time

Job summary

TekWissen LLC is seeking a Scientist II – Protein Purification to join a manufacturing lab focused on protein purification and chromatography. You will execute purification steps, operate FPLC systems, and document results to ensure product quality and compliance.

The role requires hands-on purification experience, strong data integrity, and collaboration with cross-functional teams in a regulated environment.

Qualifications

• Bachelor’s degree in a related science and 3+ years in protein purification.
• Hands-on experience with FPLC systems (Cytiva ÄKTA or Bio-Rad NGC).
• Knowledge of chromatography principles and protein chemistry.
• Experience working in a GMP/QMS environment preferred.

Responsibilities

• Perform protein purification activities following SOPs and manufacturing docs.
• Operate column chromatography, TFF, buffer prep, SDS‑PAGE and more.
• Maintain accurate batch data records and equipment logs.
• Troubleshoot routine process/equipment issues and escalate as needed.
• Contribute to process improvements and documentation updates.
• Collaborate with cross-functional teams to meet quality goals.

Skills

Protein purification

FPLC operations

Chromatography techniques

QC & QMS familiarity

Education

Bachelor's degree in Biology, Chemistry, Biochemistry, or related

Tools

Cytiva ÄKTA systems

Bio-Rad NGC systems

UNICORN software

Job description

TekWissen LLC is seeking a Scientist II – Protein Purification to join a manufacturing lab focused on protein purification and chromatography. You will execute purification steps, operate FPLC systems, and document results to ensure product quality and compliance.

The role requires hands-on purification experience, strong data integrity, and collaboration with cross-functional teams in a regulated environment.