Downstream Protein Purification Scientist - 6-Month Contract

Randstad USA; Carlsbad (CA); On-site; USD 41,000 - 51,000; Full time

Job summary

Randstad USA in Carlsbad, CA is seeking a Scientist II to lead downstream processing for therapeutic protein manufacture on a 6-month contract basis. The role requires hands-on operation of Cytiva ÄKTA UNICORN and Bio-Rad NGC systems, performing chromatography, TFF, and related QC tasks in a controlled lab.

The ideal candidate holds a Bachelor's degree in a life sciences field with 3+ years of protein purification experience and on-site work capability in ISO/GMP settings.

Qualifications

• Bachelors degree required in a life sciences field.
• 3+ years of protein purification experience in biotech manufacturing or R&D.
• Hands-on experience with Cytiva ÄKTA (UNICORN) or Bio-Rad NGC FPLC systems.
• Understanding of multiple chromatography modes (affinity, ion-exchange, SEC, HIC).
• Ability to follow strict batch records and work on-site in a controlled lab.

Responsibilities

• Purify therapeutic proteins in a controlled manufacturing lab following SOPs and documentation.
• Operate Cytiva ÄKTA UNICORN and Bio-Rad NGC platforms for downstream processes.
• Perform column chromatography (affinity, IEX, SEC, HIC), TFF, and buffer prep.
• Execute characterization assays (SDS-PAGE) and evaluate chromatograms against specs.
• Troubleshoot routine process/equipment issues and support CI/validation initiatives.
• Maintain batch records and quality documentation per QMS guidelines.

Skills

Protein purification

Laboratory skills

Documentation

Education

Bachelor's degree in Biology/Biochemistry/Chemistry or related life sciences

Tools

Cytiva ÄKTA UNICORN

Bio-Rad NGC FPLC

Job description

Randstad USA in Carlsbad, CA is seeking a Scientist II to lead downstream processing for therapeutic protein manufacture on a 6-month contract basis. The role requires hands-on operation of Cytiva ÄKTA UNICORN and Bio-Rad NGC systems, performing chromatography, TFF, and related QC tasks in a controlled lab.

The ideal candidate holds a Bachelor's degree in a life sciences field with 3+ years of protein purification experience and on-site work capability in ISO/GMP settings.