Scientist II Antibody Purification & Conjugation (2nd Shift)

Actalent; Carlsbad (CA); On-site; USD 45,000 - 51,000; Full time

Benefits offered by this job

Medical, dental & vision

401(k) Retirement Plan

Life Insurance

PTO / Vacation

Job summary

Actalent seeks a Scientist II for antibody purification and conjugation on the second shift in Carlsbad, CA. You will purify antibodies from hybridoma cultures, run affinity purification, and help produce fluorescently labeled bioconjugates for cell signaling research.

The role requires 2+ years in a life-science lab, hands-on purification with chromatography, and experience with FPLC/ÄKTA systems. Onsite work with a fast-paced production team, lifting up to 50 lbs, and strong documentation

Qualifications

• BS in a life science field required.
• 2+ years in a lab setting.
• Hands-on purification experience with chromatography-based methods.
• Working knowledge of FPLC/ÄKTA systems.
• Ability to analyze protein concentration and quality.
• Strong math and quantitative skills.
• Excellent documentation and record-keeping.

Responsibilities

• Purify monoclonal antibodies from hybridoma cultures using affinity chromatography.
• Manage multiple production runs to meet schedules and quality standards.
• Operate and maintain chromatography systems (FPLC/ÄKTA).
• Perform concentration and quality assessments using spectrophotometry.
• Support production of fluorescently labeled bioconjugates for cell signaling research.
• Prepare reagents, buffers, and materials for purification and conjugation workflows.
• Document production activities, parameters, and results accurately.
• Follow quality, safety, and compliance procedures in the lab.
• Troubleshoot chromatography, purification, and analytical issues.
• Apply lab calculations to prepare solutions and verify yields.
• Collaborate with team and cross-functional partners for goals and improvements.
• Progress from training to independent second-shift production work.

Skills

Antibody purification

FPLC/ÄKTA systems

Spectrophotometers

Laboratory math

Documentation

Troubleshooting

Written and verbal communication

Independent work after training

Physically capable (lift 50 lb)

Education

Bachelor's degree in Biology/Biochemistry/Biotech

Tools

FPLC/ÄKTA chromatography

Spectrophotometer

Job description

Actalent seeks a Scientist II for antibody purification and conjugation on the second shift in Carlsbad, CA. You will purify antibodies from hybridoma cultures, run affinity purification, and help produce fluorescently labeled bioconjugates for cell signaling research.

The role requires 2+ years in a life-science lab, hands-on purification with chromatography, and experience with FPLC/ÄKTA systems. Onsite work with a fast-paced production team, lifting up to 50 lbs, and strong documentation