Neuroscience Exploratory Scientist: iPSC Target Validation

Bristol Myers Squibb; Cambridge (MA); Presencial; USD 105 000 - 127 000; Tempo integral

Vantagens oferecidas por esta oferta de emprego

Comprehensive benefits

11 paid holidays

Flexible time off (FTO)

Resumo da oferta

Bristol Myers Squibb in Cambridge is seeking a scientist to join the neuroscience exploratory biology group. You will characterize disease-relevant biology using primary and iPSC-derived neuronal and glial systems, supporting target validation and mechanism-of-action studies to advance early-stage programs.

Responsibilities include designing and executing experiments, maintaining cultures, performing validation studies, and collaborating with computational biology and drug discovery teams to

Qualificações

• Hands-on academic, biotechnology, or pharmaceutical experience is preferred.
• Experience with mammalian cell culture and neuronal systems is advantageous.
• Strong organizational and communication skills with scientific rigor.

Responsabilidades

• Design, execute, and troubleshoot neurobiology experiments in disease-relevant pathways.
• Culture and maintain primary neuronal cultures, iPSC-derived neurons and glia.
• Perform target validation studies including genome editing and perturbations.
• Conduct mechanism-of-action studies to characterize effects on neuronal biology.
• Apply immunofluorescence and high-content imaging to assess cellular phenotypes.
• Perform qPCR, ELISA to support molecular, biochemical characterization.
• Analyze, document, and present data with rigor and reproducibility.
• Collaborate cross-functionally with computational biology, translational and drug discovery teams.
• Stay current with neuroscience literature and contribute to project strategy.

Conhecimentos

Mammalian cell culture

qPCR

ELISA

Immunofluorescence

Microscopy

High-content imaging

Genome editing

Neuroscience knowledge

Data analysis

Cross-functional collaboration

Formação académica

Bachelor's degree in Biology/Neuroscience/Pharmacology/Biochemistry or related field

Master's degree in related field

Ferramentas

JESS

Descrição da oferta de emprego

Bristol Myers Squibb in Cambridge is seeking a scientist to join the neuroscience exploratory biology group. You will characterize disease-relevant biology using primary and iPSC-derived neuronal and glial systems, supporting target validation and mechanism-of-action studies to advance early-stage programs.

Responsibilities include designing and executing experiments, maintaining cultures, performing validation studies, and collaborating with computational biology and drug discovery teams to