Senior Neuroscience In Vitro Screening Scientist

Bristol-Myers Squibb Co; United States; Hybrid; USD 105,000 - 127,000; Full time

Benefits offered by this job

Wellbeing support

Flexible Time Off (FTO)

11 paid holidays

Global Shutdown access

Job summary

Bristol Myers Squibb is seeking a detail-oriented Senior Associate Scientist, Neuroscience, In Vitro Pharmacology to advance high-throughput screening campaigns and develop scalable assays. The role supports discovery efforts in neuroscience and collaborates across automation, informatics, and validation teams.

The candidate will work with mammalian cell culture systems and contribute to go/no-go decisions through rigorous data analysis and documentation of results.

Qualifications

• Bachelor's degree in Biology, Neuroscience, Pharmacology, Biochemistry, or a related field plus 4+ years of relevant experience, Or a Master's degree plus 2+ years of relevant experience

Responsibilities

• Develop, optimize, and validate assays for high-throughput and high-content screening applications
• Execute compound screening campaigns, including cell viability and reporter-based assays
• Design and implement genetic perturbation screens (e.g., siRNA/ASO, CRISPR-based) to support therapeutic discovery
• Perform high-content imaging and automated image analysis to extract quantitative phenotypic data
• Maintain and scale mammalian cell culture systems, including cell lines and neuroscience-relevant in vitro models, to support screening throughput
• Troubleshoot assay performance issues and implement process improvements to ensure data quality and reproducibility
• Analyze large screening datasets; visualize and present results to support go/no-go decisions
• Document protocols and results in accordance with scientific and quality standards
• Partner cross-functionally with automation, informatics, and target validation teams to advance screening pipelines

Skills

High-throughput screening

Cell viability assays

High-content imaging

Data analysis

Cross-functional collaboration

Education

Bachelor's degree in Biology/ Neuroscience/ Pharmacology/ Biochemistry

Master's degree in a related field

Tools

CRISPR-based perturbation

siRNA/ASO screening

Automated image analysis software

Job description

Bristol Myers Squibb is seeking a detail-oriented Senior Associate Scientist, Neuroscience, In Vitro Pharmacology to advance high-throughput screening campaigns and develop scalable assays. The role supports discovery efforts in neuroscience and collaborates across automation, informatics, and validation teams.

The candidate will work with mammalian cell culture systems and contribute to go/no-go decisions through rigorous data analysis and documentation of results.