Neuroscience Screening Scientist — High-Throughput

Bristol Myers Squibb; Cambridge (MA); Sur place; USD 105 000 - 127 000; Plein temps

Avantages offerts par ce poste

Flexible time off

Health insurance

Paid holidays

Retirement plan

Résumé du poste

Bristol Myers Squibb in Cambridge, MA is seeking a detail-oriented scientist to support high-throughput screening in our neuroscience drug discovery group. You will develop and execute scalable assays to identify novel targets and modulators.

The role involves leading assay development, cell culture, data analysis, and cross-functional collaboration with automation and informatics teams to advance screening pipelines.

Qualifications

• Bachelor's degree in Biology, Neuroscience, Pharmacology, Biochemistry, or related field with 4+ years experience, or Master's with 2+ years.
• Experience with high-throughput/high-content screening and cell-based assays.
• Experience with genetic perturbation (siRNA/ASO, CRISPR) and data analysis.
• Experience with mammalian cell culture and in vitro neuroscience models.
• Strong data analysis/visualization and ability to work independently in cross-functional teams.

Responsabilités

• Develop, optimize, and validate assays for high-throughput screening.
• Execute compound screening campaigns including viability and reporter assays.
• Design genetic perturbation screens (siRNA/ASO, CRISPR) to support discovery.
• Perform high-content imaging and analysis to extract phenotypic data.
• Maintain and scale mammalian cell culture systems for screening throughput.
• Troubleshoot assay performance and improve data quality.
• Analyze large datasets and present go/no-go results.
• Document protocols and results to quality standards.
• Collaborate with automation, informatics, and target validation teams.

Connaissances

High-throughput screening

Cell-based assays

Genetic perturbation

Data analysis

Cross-functional collaboration

Formation

Bachelor's degree in Biology/Neuroscience/Pharmacology/Biochemistry or related field

Master's degree in related field

Outils

Automation platforms

Description du poste

Bristol Myers Squibb in Cambridge, MA is seeking a detail-oriented scientist to support high-throughput screening in our neuroscience drug discovery group. You will develop and execute scalable assays to identify novel targets and modulators.

The role involves leading assay development, cell culture, data analysis, and cross-functional collaboration with automation and informatics teams to advance screening pipelines.