Lead Computational Biologist, Pediatric Cancer Genomics

Thecentermemphis; Memphis (TN); On-site; USD 104,000 - 186,000; Full time

Job summary

St. Jude Children's Research Hospital is seeking a Senior Computational Research Scientist to study gene regulation and genome organization in pediatric cancers.

The role involves leading projects, building analytical pipelines, and collaborating with a multidisciplinary team to analyze CUTRUN, RNA-Seq, Hi-ChIP, and single-cell omics data. You will work with bedtools, samtools, and HiCPro on high-performance computing resources, present research findings, and contribute to high-impact

Qualifications

• PhD preferred with strong computational biology background.
• 7+ years of relevant experience; senior-level track record in computational research.
• Experience with large, multi-omics datasets and high-performance computing.

Responsibilities

• Lead computational research projects with increasing independence.
• Collaborate on study design under guidance of multiple PIs.
• Prioritize tasks across multiple projects and timelines.
• Develop new computational methods for regulatory circuitry in pediatric cancers.
• Integrate omics pipelines (ChIP-Seq/CUTRUN/CUTTAG, ATAC-seq, HiChIP/HiC, RNA-seq).
• Ensure data analysis adheres to lab standards and best practices.
• Identify, process, and report relevant datasets; direct data collection.
• Present findings and draft manuscripts with limited supervision.

Skills

Data analysis

Biological knowledge

Scientific communication

Collaboration

Education

Bachelor's degree in Bioinformatics or related

Master's degree or PhD preferred

Tools

bedtools

samtools

HiCPro

Job description

St. Jude Children's Research Hospital is seeking a Senior Computational Research Scientist to study gene regulation and genome organization in pediatric cancers.

The role involves leading projects, building analytical pipelines, and collaborating with a multidisciplinary team to analyze CUTRUN, RNA-Seq, Hi-ChIP, and single-cell omics data. You will work with bedtools, samtools, and HiCPro on high-performance computing resources, present research findings, and contribute to high-impact