Postdoctoral Scientist, Computational Cancer Genomics

St. Jude Children's Research Hospital; Lauderdale Courts (TN); On-site; USD 60,000 - 86,000; Full time

Job summary

St. Jude Children's Research Hospital seeks a postdoctoral research associate to lead computational projects exploring chromatin-modifying enzymes in cancer gene regulation. The role involves collaboration with Adam Durbin, Lily Guenther, and Jun Qi labs, and includes developing new methods for genome-wide data analysis.

The candidate will manage data from CUT&RUN, RNA-Seq, HiChIP, and multi-omic datasets, with emphasis on enhancers and gene regulation in pediatric cancers.

Qualifications

• Candidate must hold a doctoral degree in a quantitative field with biological context.
• Experience with chromatin and expression analysis technologies is desired.
• Strong publication record or demonstrable large-project contribution.

Responsibilities

• Lead computational research projects with increasing independence.
• Collaborate on project design with multiple PIs and labs.
• Develop new computational methods for sequencing data.
• Process, interpret, and report complex data from high-throughput experiments.
• Present findings and draft manuscripts with minimal supervision.
• Maintain regular in-person attendance for meetings and seminars.

Skills

Computational biology

Chromatin analysis

RNA-Seq

High-throughput sequencing

Education

Ph.D. in Bioinformatics, Molecular Biology, Biochemistry, Computer Science, or related field

Tools

BedTools

Samtools

HiCPro

R

Python

Job description

St. Jude Children's Research Hospital seeks a postdoctoral research associate to lead computational projects exploring chromatin-modifying enzymes in cancer gene regulation. The role involves collaboration with Adam Durbin, Lily Guenther, and Jun Qi labs, and includes developing new methods for genome-wide data analysis.

The candidate will manage data from CUT&RUN, RNA-Seq, HiChIP, and multi-omic datasets, with emphasis on enhancers and gene regulation in pediatric cancers.