LC-MS Scientist for siRNA: Method Dev & Impurity

Pace® Analytical Services; Cambridge (MA); Vor Ort; USD 92.000 - 95.000; Vollzeit

Benefits dieser Stelle

Medical

Dental and Vision

401K match

Life Insurance

Disability

PTO

HSA

Wellness program

Tuition reimbursement

Employee assistance

Parental leave

Legal coverage

Identity protection

Zusammenfassung

Pace® Analytical Services is seeking a Scientist to perform advanced analytical development focused on High-Resolution LC-MS operations and method development for siRNA and related materials. You will optimize HPLC and MS-based methods, support impurity profiling, and contribute to method qualification and regulatory filings.

The role requires a chemistry/biology background, 2–4 years in GMP labs, and strong data quality, collaboration, and communication skills.

Qualifikationen

• Bachelor’s or Master’s degree in Chemistry, Biology, or related field.
• 2-4 years of experience in a laboratory setting (GMP environment preferred).
• Excellent organizational, attention to detail, and communication skills.
• Able to handle multiple projects concurrently, self-motivated, and results driven.
• Experience with Agilent Q-ToF and the MassHunter software is a plus.
• Proficiency in Office 365 and other software preferred.

Aufgaben

• Hands-on bench work using the High-Resolution LC-MS.
• Development of chromatographic methods (HPLC) and mass spectrometric based assays for identification, characterization, and impurity determination of siRNA.
• Develop strategies for impurity profiling of new development candidates and raw materials.
• Author method development and qualification reports and SOPs for test methods.
• Evaluate suitability of new methods, and assist method qualification and validation.
• Contribute data to lead candidate testing, stability sample monitoring, OOS/deviation investigation and regulatory filing.
• Understand and apply advanced scientific principles to process and analytical development.
• Follow training to independently operate instruments and carry out routine and non-routine analyses
• Collaborate with internal and external teams to support project goals and meet research timelines

Kenntnisse

Attention to detail

Communication

Project management

Self-motivated

Results driven

Ausbildung

Bachelor’s or Master’s in Chemistry/Biology/related

Tools

Agilent Q-ToF

MassHunter

Office 365

Jobbeschreibung

Pace® Analytical Services is seeking a Scientist to perform advanced analytical development focused on High-Resolution LC-MS operations and method development for siRNA and related materials. You will optimize HPLC and MS-based methods, support impurity profiling, and contribute to method qualification and regulatory filings.

The role requires a chemistry/biology background, 2–4 years in GMP labs, and strong data quality, collaboration, and communication skills.