LC/MS Analytical Chemist

Pace Analytical Services, LLC; Cambridge (MA); On-site; USD 92,000 - 95,000; Full time

Benefits offered by this job

Competitive salaries

Medical, dental, vision

401K retirement plan

Paid time off

HSA and wellness program

Job summary

Pace Analytical Services, LLC in Cambridge, MA is seeking a Scientist to perform advanced analytical development with a focus on High-Resolution LC-MS, developing chromatographic and mass spectrometry methods for siRNA formulations and raw materials.

The role requires 2–4 years in a GMP laboratory and a Bachelor's or Master's in Chemistry or Biology, with a comprehensive benefits package and a full-time schedule from 8:00AM to 5:00PM.

Qualifications

• Bachelor's or Master's in Chemistry, Biology, or related field.
• 2–4 years of laboratory experience; GMP environment preferred.
• Strong organizational and communication skills.
• Experience with LC-MS and HPLC is a plus.

Responsibilities

• Operate High-Resolution LC-MS for analytical development.
• Develop and optimize chromatographic and MS-based methods.
• Support impurity profiling of siRNA, formulations and raw materials.
• Author method development reports and SOPs.
• Collaborate with internal and external teams to meet timelines.

Skills

LC-MS operation

HPLC method development

Mass spectrometry

SOPs & documentation

Team collaboration

Education

Bachelor's or Master's in Chemistry or Biology

Tools

Agilent Q-ToF

MassHunter

Office 365

Job description

Shift: Monday through Friday, 8:00AM - 5:00PM

Are you ready to work making the world a safer, healthier place? Join our mission to continuously move science forward; to innovate and advance all aspects of our business to improve the health and safety of our communities and lives.

Description:

The Scientist is responsible for performing advanced analytical development activities with a primary focus on hands-on operation of High-Resolution LC-MS instrumentation. This role develops and optimizes chromatographic (HPLC) and mass spectrometry-based methods to support the identification, characterization, and impurity profiling of siRNA molecules, formulations, and raw materials.

Compensation: $91,500.00 - 95,000.00 per year

Responsibilities:

• Hands-on bench work using the High-Resolution LC-MS.
• Development of chromatographic methods (HPLC) and mass spectrometric based assays for identification, characterization, and impurity determination of siRNA
• Develop strategies for impurity profiling of new development candidates and raw materials.
• Author method development and qualification reports and SOP's for test methods.
• Evaluate suitability of new methods, and assist method qualification and validation.
• Contribute data to lead candidate testing, stability sample monitoring, OOS/deviation investigation and regulatory filing.
• Understand and apply advanced scientific principles, theories, concepts, practices and standards to process and analytical development.
• Follow training to independently operate instruments and carry out routine and non-routine analyses
• Collaborate with internal and external teams to support project goals and meet research timelines

Requirements:

• Bachelor's or Master's degree in Chemistry, Biology, or related field
• 2-4 years of experience in a laboratory setting (GMP environment preferred)
• Excellent organizational, attention to detail, and communication skills.
• Ableto handle multiple projects concurrently, self-motivated, and results driven
• Experience with Agilent Q-ToF and the MassHunter software is the plus.
• Proficiency in Office 365 and other software preferred

Find Your Place at Pace - We need you - your curiosity, your talents, and your drive - to help us advance this important work.

Benefits
When you join Pace, you commit to work that makes a positive impact on our communities and our world. We commit to supporting you with benefits and perks that make a positive impact on your life. Full-time roles are eligible for our comprehensive benefits program which includes competitive salaries, medical, dental vision, 401K retirement savings plan (100% vested immediately in the employer match), life, disability and voluntary benefits, paid time off for holiday, sick and vacation days, HSA, wellness program, flexible spending accounts, tuition reimbursement, Employee Assistance program, parental leave, optional legal coverage and ID theft.

Equal Opportunity Employer

Pace provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, creed, color, religion, genetics, protected veteran status, national origin, sex, age, disability, marital status, sexual orientation, gender identity or expression, citizenship, or any other characteristic protected by federal, state or local laws. This policy applies to all terms and conditions of employment, including recruiting, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation and training.