LC/MS Analytical Chemist

Pace® Labs; Cambridge (MA); On-site; USD 92,000 - 95,000; Full time

Benefits offered by this job

Competitive salaries

Medical

Dental vision

401K retirement savings plan (100%vest

Life

Disability and voluntary benefits

Paid time off for holiday, sick andvac

HSA

Wellness program

Flexible spending accounts

Tuition reimbursement

Employee Assistance program

Parental leave

Optional legal coverage and ID theft

Job summary

Pace® Labs in Cambridge, MA seeks a Scientist to perform advanced analytical development with hands-on operation of High-Resolution LC-MS. You will develop and optimize HPLC and MS-based methods for siRNA identification, characterization, and impurity profiling of molecules, formulations, and raw materials.

Requires a Bachelor's or Master’s in Chemistry/Biology and 2–4 years in a GMP lab; strong organization, communication, and multitasking skills are essential.

Qualifications

• Bachelor's or Master's degree in Chemistry, Biology, or related field.
• 2-4 years of laboratory experience, GMP environment preferred.
• Excellent organizational and communication skills; detail-oriented.

Responsibilities

• Hands-on bench work using the High-Resolution LC-MS.
• Development of chromatographic methods (HPLC) and mass spectrometric based assays for identification, characterization, and impurity determination of siRNA.
• Develop strategies for impurity profiling of new development candidates and raw materials.
• Author method development and qualification reports and SOP's for test methods.
• Evaluate suitability of new methods, and assist method qualification and validation.
• Contribute data to lead candidate testing, stability sample monitoring, OOS/deviation investigation and regulatory filing.
• Understand and apply advanced scientific principles, theories, concepts, practices and standards to process and analytical development.
• Follow training to independently operate instruments and carry out routine and non-routine analyses.
• Collaborate with internal and external teams to support project goals and meet research timelines.

Skills

LC-MS

HPLC

Method development

Data analysis

Scientific writing

Education

Bachelor's or Master's in Chemistry, Biology, or related field

Tools

Agilent Q-ToF

MassHunter

Office 365

Job description

Shift

Monday through Friday, 8:00AM - 5:00PM

Description

The Scientist is responsible for performing advanced analytical development activities with a primary focus on hands-on operation of High-Resolution LC-MS instrumentation. This role develops and optimizes chromatographic (HPLC) and mass spectrometry-based methods to support the identification, characterization, and impurity profiling of siRNA molecules, formulations, and raw materials.

Compensation

$91,500.00 - 95,000.00 per year

Responsibilities

• Hands-on bench work using the High-Resolution LC-MS.
• Development of chromatographic methods (HPLC) and mass spectrometric based assays for identification, characterization, and impurity determination of siRNA.
• Develop strategies for impurity profiling of new development candidates and raw materials.
• Author method development and qualification reports and SOP's for test methods.
• Evaluate suitability of new methods, and assist method qualification and validation.
• Contribute data to lead candidate testing, stability sample monitoring, OOS/deviation investigation and regulatory filing.
• Understand and apply advanced scientific principles, theories, concepts, practices and standards to process and analytical development.
• Follow training to independently operate instruments and carry out routine and non-routine analyses.
• Collaborate with internal and external teams to support project goals and meet research timelines.

Requirements

• Bachelor's or Master's degree in Chemistry, Biology, or related field.
• 2-4 years of experience in a laboratory setting (GMP environment preferred).
• Excellent organizational, attention to detail, and communication skills.
• Able to handle multiple projects concurrently, self-motivated, and results driven.
• Experience with Agilent Q-ToF and the MassHunter software is the plus.
• Proficiency in Office 365 and other software preferred.

Find Your Place at Pace - We need you - your curiosity, your talents, and your drive - to help us advance this important work.

Benefits

Full-time roles are eligible for our comprehensive benefits program.

• Competitive salaries
• Medical
• Dental vision
• 401K retirement savings plan (100% vested immediately in the employer match)
• Life
• Disability and voluntary benefits
• Paid time off for holiday, sick and vacation days
• HSA
• Wellness program
• Flexible spending accounts
• Tuition reimbursement
• Employee Assistance program
• Parental leave
• Optional legal coverage and ID theft

Equal Opportunity Employer

Pace® provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, creed, color, religion, genetics, protected veteran status, national origin, sex, age, disability, marital status, sexual orientation, gender identity or expression, citizenship, or any other characteristic protected by federal, state or local laws. This policy applies to all terms and conditions of employment, including recruiting, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation and training.

Pace® makes the world a safer, healthier place. We partner with clients to provide the service, science, and laboratory data needed to make critical decisions that benefit us all. Through a nationwide laboratory network, Pace® advances the science of businesses, industries, consulting firms, government agencies, and others. More at PACELABS.com.