LC/MS Analytical Chemist

Pacelabs; Cambridge (MA); On-site; USD 92,000 - 95,000; Full time

Benefits offered by this job

Medical

Dental and vision

401K retirement plan

Paid time off

HSA and wellness program

Job summary

Pacelabs is seeking a dedicated laboratory scientist to support development and validation of chromatographic methods and mass spectrometric assays for siRNA with GMP experience.

The role involves hands-on bench work with High-Resolution LC-MS, method development, impurity profiling strategies, and collaboration with internal and external teams to meet research timelines. Monday–Friday, 8:00AM–5:00PM in Cambridge.

Qualifications

• Bachelor’s or Master’s degree in Chemistry, Biology, or related field.
• 2–4 years of experience in a laboratory setting (GMP environment preferred).
• Excellent organizational, attention to detail, and communication skills; able to handle multiple projects.
• Experience with Agilent Q-ToF and MassHunter software is a plus.
• Proficiency in Office 365 and other software is preferred.

Responsibilities

• Hands-on bench work using the High-Resolution LC-MS.
• Develop chromatographic methods (HPLC) and MS-based assays for siRNA analysis.
• Develop impurity profiling strategies for development candidates and raw materials.
• Author method development and qualification reports and SOPs for test methods.
• Evaluate suitability of new methods and assist with qualification/validation.
• Contribute data to lead candidate testing, stability monitoring, and regulatory filings.
• Apply advanced scientific principles to process and analytical development.
• Follow training to operate instruments and carry out analyses.
• Collaborate with internal and external teams to meet timelines.

Skills

GMP experience

Attention to detail

Communication skills

Self-motivated

Results driven

Education

Bachelor’s or Master’s in Chemistry/Biology

Tools

Agilent Q-ToF

MassHunter

Office 365

Job description

Shift: Monday through Friday, 8:00AM - 5:00PM Are you ready to work making the world a safer, healthier place? Join our mission to continuously move science forward; to innovate and advance all aspects of our business to improve the health and safety of our communities and lives.

Compensation: $91,500.00 - 95,000.00 per year

Responsibilities

• Hands-on bench work using the High-Resolution LC-MS.
• Development of chromatographic methods (HPLC) and mass spectrometric based assays for identification, characterization, and impurity determination of siRNA
• Develop strategies for impurity profiling of new development candidates and raw materials.
• Author method development and qualification reports and SOP’s for test methods.
• Evaluate suitability of new methods, and assist method qualification and validation.
• Contribute data to lead candidate testing, stability sample monitoring, OOS/deviation investigation and regulatory filing.
• Understand and apply advanced scientific principles, theories, concepts, practices and standards to process and analytical development.
• Follow training to independently operate instruments and carry out routine and non-routine analyses
• Collaborate with internal and external teams to support project goals and meet research timelines.

Requirements

• Bachelor’s or Master’s degree in Chemistry, Biology, or related field
• 2-4 years of experience in a laboratory setting (GMP environment preferred)
• Excellent organizational, attention to detail, and communication skills. Able to handle multiple projects concurrently, self-motivated, and results driven
• Experience with Agilent Q-ToF and the MassHunter software is the plus.
• Proficiency in Office 365 and other software preferred

Benefits

Full-time roles are eligible for our comprehensive benefits program which includes

• competitive salaries
• medical
• dental vision
• 401K retirement savings plan (100% vested immediately in the employer match)
• life
• disability and voluntary benefits
• paid time off for holiday
• sick and vacation days
• HSA
• wellness program
• flexible spending accounts
• tuition reimbursement
• Employee Assistance program
• parental leave
• optional legal coverage and ID theft

Equal Opportunity Employer

Pace® provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, creed, color, religion, genetics, protected veteran status, national origin, sex, age, disability, marital status, sexual orientation, gender identity or expression, citizenship, or any other characteristic protected by federal, state or local laws. This policy applies to all terms and conditions of employment, including recruiting, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation and training.

Pace® makes the world a safer, healthier place. We partner with clients to provide the service, science, and laboratory data needed to make critical decisions that benefit us all. Through a nationwide laboratory network, Pace® advances the science of businesses, industries, consulting firms, government agencies, and others. More at PACELABS.com.