High-Res LC-MS Scientist for siRNA Impurity Profiling

Pace Analytical Life Sciences; Cambridge (MA); On-site; USD 92,000 - 95,000; Full time

Job summary

Pace Analytical Life Sciences in Cambridge, MA is seeking a Scientist to perform advanced analytical development with hands-on operation of High-Resolution LC-MS. You will develop chromatographic methods (HPLC) and MS-based assays for identification, characterization, and impurity profiling of siRNA molecules, formulations, and raw materials.

Responsibilities include method development and qualification reports, SOPs, evaluating new methods, and collaborating with internal and external teams to

Qualifications

• Bachelor's or Master’s degree in Chemistry, Biology, or related field.
• 2–4 years of lab experience in a GMP environment preferred.
• Experience with Agilent Q-TOF and MassHunter is a plus.

Responsibilities

• Perform advanced analytical development with hands-on high-resolution LC-MS.
• Develop and optimize HPLC and MS-based methods for identification and impurity profiling of siRNA.
• Author method development and qualification reports and SOPs.
• Collaborate with internal and external teams to meet project timelines in a GMP environment.
• Support regulatory filings and data integrity.

Skills

Analytical chemistry

HPLC/LC-MS operation

Excellent communication

Strong organization

Education

Bachelor’s or Master’s degree in Chemistry, Biology, or related field

Tools

Agilent Q-TOF

MassHunter

Office 365

Job description

Pace Analytical Life Sciences in Cambridge, MA is seeking a Scientist to perform advanced analytical development with hands-on operation of High-Resolution LC-MS. You will develop chromatographic methods (HPLC) and MS-based assays for identification, characterization, and impurity profiling of siRNA molecules, formulations, and raw materials.

Responsibilities include method development and qualification reports, SOPs, evaluating new methods, and collaborating with internal and external teams to