Immunology Biomarker Lead — Translational Science

MSD

Boston (MA)

Hybrid

USD 191,000 - 300,000

Full time

14 days+

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Job summary

MSD in Boston is seeking a Principal Scientist (Director) to lead Immunology Biomarker strategies across the development portfolio, shaping hypotheses and endpoints to inform decision-making. The role requires deep immunology expertise, strategic thinking, and ability to lead matrixed teams, with responsibilities spanning discovery through late-stage development and external communications.

The candidate will collaborate across translational medicine, regulatory, bio-statistics, and data

Qualifications

  • PhD or MD with 7+ years in Immunology; MS with 10+ years; BS with 14+ years.
  • Experience in autoimmune diseases R&D and translational medicine preferred.
  • Proven ability to lead matrixed biomarker programs across development stages.
  • Strong analytical, communication and cross-functional collaboration skills.

Responsibilities

  • Lead and shape integrated biomarker strategies across discovery, early- and late-stage programs with explicit linkage to development decisions.
  • Serve as biomarker strategy lead within cross-functional program teams and governance forums.
  • Inform portfolio strategy by biomarker-driven insights for target validation and patient selection.
  • Translate disease biology and mechanism of action into clinically actionable biomarker strategies.
  • Drive selection and application of innovative biomarker approaches aligned with clinical utility.

Skills

Biomarker development
Biomarker discovery
Biomarker identification
Biomarker qualification
Biomarkers
Clinical development
Clinical research
Immunology
Immuno-Oncology
Inflammatory diseases
Pharmacodynamics
Translational medicine

Education

PhD or MD in Immunology/Biology or related STEM
MS with 10+ years in Immunology
BS with 14+ years experience

Job description

MSD in Boston is seeking a Principal Scientist (Director) to lead Immunology Biomarker strategies across the development portfolio, shaping hypotheses and endpoints to inform decision-making. The role requires deep immunology expertise, strategic thinking, and ability to lead matrixed teams, with responsibilities spanning discovery through late-stage development and external communications.

The candidate will collaborate across translational medicine, regulatory, bio-statistics, and data

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