Strategic Immunology Biomarker Lead - Principal Scientist

Merck

Cambridge (MA)

Hybrid

USD 190,000 - 230,000

Full time

18 hours ago

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Job summary

Merck in Cambridge, MA seeks a Principal Scientist (Director) to lead Immunology Biomarker strategies within Translational Clinical Biomarkers. You will design and guide biomarker programs, linking drug mechanism to clinical endpoints and decision-making across development lifecycles.

The role requires deep immunology expertise, strong data interpretation, and leadership to align multiple functions in a fast-paced environment, with cross-disciplinary collaboration and external engagement as

Qualifications

Asking for PhD/MD with 7+ years in Immunology; MS with 10+ years; BS with 14+ years in related fields.
Deep expertise in immune-mediated/inflammatory diseases including rheumatology or GI; autoimmune R&D preferred.
Strong cross-functional leadership and ability to drive translational strategies.

Responsibilities

Lead and shape immunology biomarker strategies across programs with clear hypotheses and endpoints.
Represent biomarker strategy in governance forums and cross-functional teams.
Translate biology into clinically actionable biomarker plans and surrogate endpoints.
Drive innovative biomarker approaches aligned with clinical utility and decisions.
Collaborate with discovery, translational medicine, regulatory, bio-stats and data science teams.