GMP Cell Culture Operations Lead

Vertex Pharmaceuticals LLC; Boston (MA); On-site; USD 120,000 - 150,000; Full time

Job summary

Vertex Pharmaceuticals LLC in Boston, MA seeks a Manufacturing Operations Supervisor to lead GMP cell processing teams on 2nd shift. You will oversee 2–8 direct reports, ensure cGMP compliance, manage scheduling, and drive cross-functional quality initiatives in a cleanroom environment.

The role requires 3+ years in cell culture with supervisory experience and strong problem-solving skills, plus proficiency with SOPs, batch records, and essential software. On-site position with full benefits.

Qualifications

• Minimum 3 years of cell culture experience (adherent & suspension)
• Strong GMP knowledge and leadership experience
• Experience supervising 2–8 direct reports
• Familiarity with 21 CFR 210/211 and 21 CFR 820 quality systems
• Ability to manage schedules and projects across a manufacturing team
• Proficient in SOPs, batch records, and document control

Responsibilities

• Builds and develops an efficient team of 2-8 direct reports to produce clinical cellular product per cGMP standards.
• Ensures cGMP compliance through team education and oversight.
• Manages personnel scheduling in coordination with Manufacturing leadership.
• Leads projects, tracks timelines, and leads group meetings.
• Collaborates with cross-functional stakeholders on quality events, deviations, CAPAs, and risk assessments.
• Creates and updates SOPs and batch records for manufacturing.
• Receives and manages equipment alarms; acts as technical SME.
• Demonstrates Vertex leadership behaviors: Lead by example, teach & develop, collaboration, breakthrough results.

Skills

GMP leadership

Cell culture

Supervisory experience

Quality systems

Project coordination

Troubleshooting

SOPs/documentation

Computer skills

Tools

Microsoft Word

Microsoft Excel

Microsoft Project

Outlook

Job description

Vertex Pharmaceuticals LLC in Boston, MA seeks a Manufacturing Operations Supervisor to lead GMP cell processing teams on 2nd shift. You will oversee 2–8 direct reports, ensure cGMP compliance, manage scheduling, and drive cross-functional quality initiatives in a cleanroom environment.

The role requires 3+ years in cell culture with supervisory experience and strong problem-solving skills, plus proficiency with SOPs, batch records, and essential software. On-site position with full benefits.