Director of DMPK & Modality Innovation

VidaVinci, Inc.; Watertown (MA); On-site; USD 260,000 - 380,000; Full time

Job summary

VidaVinci, Inc. in Watertown, MA is seeking an experienced DMPK leader to partner across chemistry, biology and computation, applying ADME/PK expertise to guide modality design and program progression from hit to IND-enabling studies.

The role requires strong collaboration, scientific judgment, and the ability to communicate findings to leadership and external partners, with responsibility for mentoring DMPK staff.

Qualifications

• Ph.D. with 10+ years in industry DMPK.
• Deep small-molecule DMPK expertise with translational insight.
• Experience enabling discovery programs from early stages through IND-enabling studies.
• Broad expertise across in vitro ADME, in vivo PK, metabolism and PK/PD modeling.
• Thrives in fast-paced, timeline-driven environments and communicates clearly.

Responsibilities

• Drive DMPK strategy across modality platforms and programs.
• Lead in vitro ADME, metabolism, transporters, and DDI assessments.
• Direct in vivo PK and translational PK/PD modeling and dose projections.
• Partner with medicinal chemistry to guide DMPK-driven design.
• Oversee bioanalytical strategy and CRO management.
• Communicate findings to leadership and contribute to IND documentation.
• Mentor DMPK staff and scientific partners.

Skills

DMPK leadership

ADME/PK expertise

Translational modeling

PK/PD modeling

Team mentorship

Education

Ph.D. in relevant field

Job description

VidaVinci, Inc. in Watertown, MA is seeking an experienced DMPK leader to partner across chemistry, biology and computation, applying ADME/PK expertise to guide modality design and program progression from hit to IND-enabling studies.

The role requires strong collaboration, scientific judgment, and the ability to communicate findings to leadership and external partners, with responsibility for mentoring DMPK staff.