Executive Director, Biotherapeutics DMPK-BA (On-Site)

Vertex Pharmaceuticals Incorporated; Boston (MA); In loco; USD 268.000 - 402.000; Tempo pieno

Vantaggi offerti da questo lavoro

On-Site with flexibility

Descrizione del lavoro

Vertex Pharmaceuticals Incorporated seeks an Executive Director, Biotherapeutics DMPK-Bioanalysis (DMPK-BA) to lead strategy across Boston and Seattle. This role guides PK, bioanalysis, ADME and translational PKPD inputs from discovery to development, shaping program decisions and portfolio direction.

The ideal candidate brings deep DMPK-BA expertise in multiple biotherapeutic modalities and demonstrable leadership, with a track record of regulatory submissions and cross-functional influence.

Competenze

• PhD in Pharmacokinetics, Biochemistry, Biology, or related field.
• 15+ years of industry experience at management level.
• Experience leading DMPK-BA teams across multiple therapeutic modalities.
• Deep expertise in PK, ADME, bioanalysis, immunogenicity and translational PKPD for biologics.
• Excellent communication and cross-site collaboration skills.
• Experience preparing regulatory submissions and engaging health authorities.
• Strong leadership and mentoring abilities.

Mansioni

• Develop vision and strategy for Biotherapeutics DMPK-BA teams across Boston and Seattle.
• Define and execute scientific strategies from discovery through clinical development.
• Communicate findings to senior leadership and governance bodies.
• Build collaborations with Biology, Preclinical Safety, Clinical Pharmacology, CMC and other R&D disciplines.
• Implement innovative technologies to enhance impact and efficiency.
• Provide scientific and managerial leadership for prioritizing deliverables.
• Ensure regulatory compliance for DMPK documents and reports.
• Hire, develop, and retain key talent.
• Develop sourcing strategies and manage resource allocation.
• Participate in business development review.

Conoscenze

DMPK-BA management

PK/ADME

Bioanalysis

Immunogenicity

Translational PKPD

Communication

Innovation

Regulatory experience

Leadership

Formazione

PhD in Pharmacokinetics, Biochemistry, Biology, or related field

Descrizione del lavoro

Vertex Pharmaceuticals Incorporated seeks an Executive Director, Biotherapeutics DMPK-Bioanalysis (DMPK-BA) to lead strategy across Boston and Seattle. This role guides PK, bioanalysis, ADME and translational PKPD inputs from discovery to development, shaping program decisions and portfolio direction.

The ideal candidate brings deep DMPK-BA expertise in multiple biotherapeutic modalities and demonstrable leadership, with a track record of regulatory submissions and cross-functional influence.