Cell Assay Lead: Kinase Signaling & Cell Biology

Thecentermemphis; Memphis (TN); On-site; USD 138,000 - 262,000; Full time

Job summary

St. Jude Children's Research Hospital seeks an experienced Senior Scientist to lead cell-based assays in the Blue Sky Kinases project.

You will guide junior staff, design experiments translating kinase structure into cellular effects, and collaborate across disciplines to advance kinase biology and disease mechanism insights. This role emphasizes interdisciplinary work, deep expertise in cell biology, and the translation of in vitro findings to cellular function within a world-class research

Qualifications

• Bachelor's degree in relevant scientific area required.
• PhD preferred.
• Fifteen (15) years of relevant work experience required with a Bachelor's degree; 13 years with a Master’s; 10 years with a PhD.

Responsibilities

• Research kinase-mediated signaling pathways and cellular outcomes for assigned projects.
• Interface with cell-based assays and structural biology researchers to select cellular assays.
• Develop strategies for a wide spectrum of cell-based assays including phosphorylation, localization, and RNA abundance.
• Lead and mentor a team of scientists and review experimental data for optimization and troubleshooting.
• Implement and troubleshoot diverse cell-based phenotypic assays: viability, apoptosis, autophagy, migration, differentiation.

Skills

Kinase signaling

Cell culture

Protein expression

Data analysis

Education

Bachelor's degree in sciences

PhD preferred

Tools

qRT-PCR

Flow cytometry

Western blotting

Job description

St. Jude Children's Research Hospital seeks an experienced Senior Scientist to lead cell-based assays in the Blue Sky Kinases project.

You will guide junior staff, design experiments translating kinase structure into cellular effects, and collaborate across disciplines to advance kinase biology and disease mechanism insights. This role emphasizes interdisciplinary work, deep expertise in cell biology, and the translation of in vitro findings to cellular function within a world-class research