Senior Scientist – Cell-Based Kinase Assays

St. Jude Children's Research Hospital; Memphis (TN); On-site; USD 104,000 - 186,000; Full time

Job summary

St. Jude Children's Research Hospital in Memphis, TN, seeks a Cell Assay Senior Scientist to advance the Blue Sky Kinases initiative.

The role focuses on translating kinase structure insights into functional cellular effects, using diverse cell models and high- to low-throughput platforms for kinase inhibitors. The candidate will apply molecular biology, biochemistry, and cell culture expertise to study multiple kinases, validate structural findings, and uncover novel kinase biology under the

Qualifications

• Minimum formal education of a bachelor’s degree in a scientific field.
• Experience in cell-based assays and kinase-related studies.
• Strong background in molecular biology and biochemistry techniques.

Responsibilities

• Research kinase-mediated signaling pathways and cellular outcomes.
• Identify appropriate cell-based assays for structure-guided perturbations.
• Develop strategies for cell-based assays including phosphorylation and protein analysis.
• Develop phenotypic assays and optimize cell-based protocols.
• Perform statistical analysis and interpret results with the team.
• Communicate findings to collaborators and document results.

Skills

Molecular biology

Cell culture

Biochemistry

Protein expression

Data analysis

qRT-PCR

Education

Bachelor's degree

PhD preferred

Tools

qRT-PCR

Western blot

Flow cytometry

Transfection

Immunoprecipitation

Job description

St. Jude Children's Research Hospital in Memphis, TN, seeks a Cell Assay Senior Scientist to advance the Blue Sky Kinases initiative.

The role focuses on translating kinase structure insights into functional cellular effects, using diverse cell models and high- to low-throughput platforms for kinase inhibitors. The candidate will apply molecular biology, biochemistry, and cell culture expertise to study multiple kinases, validate structural findings, and uncover novel kinase biology under the