Senior Scientist (Protein Analysis unit)

CHUGAI PHARMABODY RESEARCH PTE. LTD.; Singapore; On-site; SGD 70,000 - 100,000; Full time

Job summary

A biotechnology company in Singapore is seeking a Senior Scientist specializing in protein analysis to lead antibody characterization across discovery and optimization. Responsibilities include leading antibody binding affinity screening, executing analyses, and collaborating with multidisciplinary teams. A Ph.D. in a relevant field is required along with expertise in protein-protein interactions and various biophysical techniques. Interested applicants should contact [e-mail] with their resume and salary expectations.

Qualifications

• Ph.D. in Biophysics, Biochemistry, or related field with 0 – 2+ years of experience.
• Experience in monoclonal antibody drug discovery preferred.
• Proficiency in spoken and written English.

Responsibilities

• Lead antibody binding affinity screening using SPR.
• Plan and execute antibody/ligand binding analyses.
• Support projects from high-throughput screening to developability.

Skills

Protein-protein interaction analysis

Binding kinetic and affinity analysis

Problem-solving skills

Data analysis

Education

Ph.D. in a relevant scientific field

Tools

SPR

BLI

Column chromatography

Biophysical characterization techniques

Job description

Senior Scientist, Protein Analysis

We are seeking a Senior Scientist with deep expertise in protein analysis to lead antibody characterization across discovery and optimization, from high-throughput screening through developability. Reporting to the Research Manager, you will drive assay development and data generation, collaborate closely with cross-functional teams, and contribute to novel protein analysis technology development. After initial training, you are expected to independently manage antibody analysis.

Key Responsibilities

• Lead antibody binding affinity screening using SPR.
• Plan and execute antibody/ligand binding analyses.
• Plan and conduct biophysical analyses to evaluate physicochemical properties of antibodies.
• Assess developability and manufacturability of antibody drug candidates.
• Support projects from high-throughput screening to late-stage developability assessment, collaborating with multidisciplinary teams to achieve project milestones.
• Contribute to the development and implementation of novel protein analysis technologies.

Required Qualifications

• Ph.D. in Biophysics, Biochemistry, Structural Biology, Biomedical Science, Chemical Biology, Biotechnology, Life Science, or Pharmaceutical Science, or a related scientific field with 0 – 2+ years of relevant industry or research experience, preferably in monoclonal antibody drug discovery.
• Strong expertise in protein-protein interaction analysis, binding kinetic and affinity analysis, physicochemicalcharacterization of monoclonal antibodies.
• Hands‑on experience in at least one of the following areas:
  • Protein–protein interaction analysis (SPR, BLI, GCI)
  • Column chromatography (ion-exchange, size-exclusion, reversed-phase)
  • Biophysical characterization (DLS, DSC, solubility, viscosity, stability testing)
  • Protein LC–MS analysis
• Ability to work in a fast‑paced, collaborative environment
• Strong problem‑solving skills and ability to work independently and in team settings
• Proficiency in spoken and written English.

The ideal candidate

• Demonstrates a strong passion for medical science and drug innovation.
• Capable of independently running and troubleshooting assays, optimizing methods, and adopting new technologies.
• Ensures data integrity, safety, and compliance with SOPs.
• Skilled in data analysis, visualization, and clear communication to diverse audiences.
• Effective in planning, meeting deadlines, and collaborating across teams.

Application procedures

Interested applicants are invited to email their detailed resume, qualifications, availability, current and expected salary to: [e-mail]

For more information regarding our Company, you may refer to our website at: http://chugai-pharmabody.com/

We regret that only short-listed candidates will be notified