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At Apoha, we're building Liquid Brain—a natural computer made of soft matter that senses, computes, and learns by physically interacting with molecules. It’s the early form of a non-biological lifeform—an intelligence that feels, interprets, and eventually responds to the material world. Apoha sits at the cutting edge of biophysics, ML, and materials science, producing unique datasets to help design and formulate materials.

At Apoha, software engineering isn’t just about writing code — it’s about creating the foundation for a breakthrough technology to thrive. As an engineer here, you’ll help shape how the world’s top scientists and researchers interact with the Liquid Brain. This is a rare opportunity to leave your fingerprint on a domain-defining platform, working in a fast-paced, intellectually rigorous, and mission-driven environment.

We’re looking for a Senior Full Stack Engineer who thrives on autonomy, ownership, and creative problem-solving. This role is ideal for someone who wants to help define the architecture, culture, and best practices of a growing team — someone who’s just as excited by writing clean, scalable code as they are by collaborating with scientists to bring a fundamentally new technology to life.

What You’ll Do

• Own and drive major parts of our software stack — from design and architecture to implementing scalable solutions across the tech stack.
• Lead the design and implementation of a novel data analysis platform that brings together cutting-edge analytics, ML models, and interactive visualizations.
• Root-cause and resolve issues across the entire stack in a fast-paced environment.
• Collaborate directly with our scientific and data science teams, translating research needs into product features that make a direct impact for our customers.
• Push the envelope of how engineering and science can work together to build a truly unique technology.

What We’re Looking For

• Experience as a full stack engineer working with large complex systems.
• Strong sense of agency, resourcefulness, and ownership is absolutely essential — you care deeply about both the what and the how.
• Proven expertise in at least a few of the following areas: designing scalable services, cloud infrastructure, API design and implementation, database design, and front-end frameworks.
• Ability to design and implement features end-to-end, with an eye for shipping fast, iterating often, and balancing pragmatism with long-term scalability.
• Curiosity and enthusiasm for learning new technologies and deeply scientific concepts.
• Bonus: exposure to Python, Django, PostgreSQL, AWS, Kubernetes and/or containerized deployments, nextJS, React — but we care more about your mindset than the exact tech stack you have previously worked on.

Why Join Us?

We’re Apoha, the team behind the Liquid Brain. We're pioneering Sensory Intelligence by decoding molecular behaviour. The first step in our journey to giving machines the senses they never had? Building a Liquid Brain platform capable of improving life-saving drugs, by assessing the developability of antibodies earlier (those proteins our immune system makes to fight off bacteria and viruses).

We’re a group of scientists, engineers, and operators who’ve built and launched successful products at Goldman Sachs, Apple, Amazon, and published 50+ high impact research papers across biophysics, materials science, and thermodynamics—and been featured by Scientific American as one of “13 Discoveries That Could Change Everything”. At Apoha, science isn’t just the foundation of our product—it’s woven into our every day. Whether it’s a journal club over coffee, a spirited scientific discussion unravelling a complex problem, or a full-company Quarter Demo Day that sparks wild new ideas, we’ve built a place where academic rigor meets startup energy.

Our team is small, flat, and talent-dense across disciplines. We gravitate towards people who are collaborative, curious, and take pride in owning their work end-to-end. We enjoy spirited debate, thinking way beyond the state of the art, and building products that could change how we understand biological materials—forever.

We believe in the power of on-site collaboration, and our UK-based team works together in our London office to foster creativity, speed, and connection.

Our investors include Redalpine, Acequia Capital, Seedcamp, Nucleus Capital, Plug and Play, Wilbe and others—and we’re just getting started.

What We Offer

• Competitive compensation + stock options.
• Private health insurance.
• Bi-weekly team lunches + regular socials.
• The rare chance to shape the DNA of a company.
• Access to cutting-edge science, a stellar team, and the chance to change the game.

Application Process – Show Us What You’ve Got

We’ve designed an interactive challenge to kick off the application.

To get started, send an empty POST request to this endpoint - api/v2/external-tests/hello-apoha at the URL - https://api-v2.test.appapohacom

We will get back to you to schedule the first technical interview with our team shortly after reviewing your submission! In case of any questions please reach out to [emailprotected].

At Apoha, we are committed to fostering a diverse and inclusive workplace. We strongly encourage applications from candidates of all backgrounds, including those from underrepresented groups in tech and science.