Senior Scientist I — Biopharma Characterisation & MS

IMMUNOCORE LTD

Stanford in the Vale

On-site

GBP 60,000 - 90,000

Full time

3 days ago
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Job summary

Immunocore is seeking a Senior Scientist I - Characterisation to advance protein and biologics characterisation using LC-MS/MS and peptide mapping. You will lead extensive testing of biomolecules expressed in microbial and mammalian systems and contribute to method development for the company’s biopharmaceutical products.

The role requires strong expertise in MS, HPLC mapping and glycosylation analysis, with a proven track record in a bench biopharma laboratory.

Qualifications

  • Essential: Experience in development of HPLC based peptide mapping methods and MS characterisation of recombinant proteins/antibodies.
  • Essential: Glycosylation analysis of recombinant proteins/antibodies.
  • Essential: Independently coordinated extensive testing of protein biomolecules.
  • Essential: Characterisation of proteins expressed in microbial and mammalian systems.
  • Essential: Understanding of expected post-translational modifications.

Responsibilities

  • Develop HPLC-based peptide mapping methods and MS characterisation for biologics.
  • Characterise protein biomolecules in microbial and mammalian systems.
  • Lead testing programs and contribute to protocol and report writing.
  • Present findings to internal teams and partners.
  • Maintain laboratory records and ensure EHS compliance.

Skills

HPLC peptide mapping
Mass spectrometry
Glycosylation analysis
Protein characterization
Post-translational modifications
Biopharmaceutical lab experience
Assay development
Team collaboration
Project leadership
Scientific communication

Education

BSc/MSc in biochemistry/biotechnology
PhD in related discipline

Tools

LC-MS/MS
Chromatography
Electrophoresis

Job description

Immunocore is seeking a Senior Scientist I - Characterisation to advance protein and biologics characterisation using LC-MS/MS and peptide mapping. You will lead extensive testing of biomolecules expressed in microbial and mammalian systems and contribute to method development for the company’s biopharmaceutical products.

The role requires strong expertise in MS, HPLC mapping and glycosylation analysis, with a proven track record in a bench biopharma laboratory.

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