Senior Scientist I: Biopharma Protein Characterisation & MS

IMMUNOCORE LTD

Ashton Keynes

On-site

GBP 60,000 - 85,000

Full time

3 days ago

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Job summary

Immunocore is seeking a Senior Scientist I - Characterisation within its CMC group to drive protein characterisation and mass spectrometry analyses for biopharmaceutical products. The role focuses on peptide mapping (LC-MS/MS), glycosylation analysis, and developing analytical methods to support process development.

You will mentor colleagues, contribute to protocols and reports, and present findings to senior management and partners.

Qualifications

Experience in development of HPLC based peptide mapping methods and mass spectrometric characterisation of recombinant proteins or antibodies.
Experience of glycosylation analysis of recombinant proteins or antibodies.
Independently coordinated extensive testing of protein biomolecules.
Experienced in the characterisation of proteins expressed in both microbial and mammalian systems.

Responsibilities

Design and carry out biochemical characterisation, chemical stability and comparability studies of biologics/drug products.
Support writing study protocols and reports.
Independently testing and leading lines of investigation; propose new experiments based on data.
Present detailed scientific findings to internal and external audiences.