Research Associate, Histology

Flagship Pioneering, Inc.; Cambridge; On-site; GBP 30,000 - 45,000; Full time

Job summary

A pioneering biotechnology company in Cambridge is seeking a Research Associate in Histology. The role involves performing histological techniques and collaborating with scientists on R&D programs. Candidates should have a BSc or MSc in relevant fields and hands-on experience in various histology processes. The company fosters an inclusive work environment, passionate about scientific advancement and problem-solving.

Qualifications

• 2+ years of relevant post-graduation experience.
• Experience in a high-throughput laboratory environment.
• Knowledge of immunology and RNA biology.

Responsibilities

• Perform histological techniques including tissue fixation and staining.
• Collaborate with assay development on process optimization.
• Support implementation of novel target discovery platforms.

Skills

Hands-on experience in histology processes

Knowledge of HTA regulations

Molecular biology techniques

Education

BSc or MSc in biochemistry, molecular or microbiology

Tools

Laboratory information management systems (Benchling preferred)

Job description

Company Summary

Quotient Therapeutics develops breakthrough medicines informed by natural somatic genetic diversity present in patients. Through our work in somatic genomics, we are forging a new status quo for biopharma research and development across a broad pipeline of internal and partnered programs. We are a privately held, early-stage company and are an equal opportunity employer.

The company was founded by Flagship Pioneering, an innovative enterprise that conceives, creates, resources, and grows first-in-category life sciences companies. Flagship Pioneering has created over 100 groundbreaking companies over the past twenty years, all of which are pioneering novel and proprietary biological, industrial, and engineering approaches to solve major needs in human health and sustainability. These companies include Moderna (MRNA), Generate Biomedicines, Sana Biotechnology (SANA), Tessera Therapeutics, Evelo Biosciences (EVLO), Indigo Agriculture, Seres Therapeutics (MCRB), and Syros Pharmaceuticals (SYRS).

Position Summary

We are seeking a motivated, enthusiastic Research Associate in Histology to join our passionate team. The candidate will work closely with our team of scientists to advance multiple aspects of the R&D programs at Quotient Therapeutics. The successful candidate will be a self-starter, able to thrive in a fast-paced, action-oriented team environment and have a clear passion for the science we are doing. They will have demonstrated evidence of agility in their scientific work and an overt attitude of positivity when facing challenges. They will be dedicated to learning and development, embrace feedback and be open to working outside their comfort zone.

Key Responsibilities

• Perform histological techniques including tissue fixation, embedding, sectioning, immunohistochemistry, and specialized staining protocols
• Collaborate with the assay development team on process optimization and method transfers
• Support the implementation of novel target discovery platforms, protocols, and other assays
• Maintain compliance with regulatory requirements and quality standards, including the Human Tissue Act and COSHH
• Collaborate and communicate with other team members across various functional areas

Key Skills and Experience

Essential

• BSc or MSc degree in biochemistry, molecular or microbiology, or related field
• 2+ years of relevant post-graduation experience
• Hands-on experience in taking tissue through multiple histology processes including embedding, sectioning, and staining
• Knowledge and experience of working under HTA regulations

Desirable

• Use of laboratory information management systems (Benchling preferred)
• Experience of working in a high-throughput laboratory environment
• Experience in a variety of molecular biology and biochemistry techniques, including: DNA extraction, NGS library preparation, tissue sectioning and laser capture microdissection.
• Knowledge of immunology, mRNA expression analysis, DNA/RNA purification, RNA biology, next generation sequencing

About Flagship

Flagship Pioneering is a bioplatform innovation company that invents and builds platform companies, each with the potential for multiple products that transform human health or sustainability. Since its launch in 2000, Flagship has originated and fostered more than 100 scientific ventures, resulting in more than $90 billion in aggregate value. Many of the companies Flagship has founded have addressed humanity's most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture. Flagship has been recognized twice on FORTUNE's "Change the World" list, and has been named to Fast Company's annual list of the World's Most Innovative Companies.

Learn more about Flagship at www.flagshippioneering.com.

Flagship Pioneering and our ecosystem companies are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.

EEO statement note: At Flagship, we recognize there is no perfect candidate. If you have some of the experience listed above but not all, please apply anyway. Experience comes in many forms, skills are transferable, and passion goes a long way. We are dedicated to building diverse and inclusive teams and look forward to learning more about your unique background.

Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, "FSP") do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering's internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.