Senior Scientist, Biomarker Translation & Assay Development

CTC Resourcing Solutions AG; Basel-Stadt; On-site; CHF 110,000 - 150,000; Full time

Job summary

CTC Resourcing Solutions AG is seeking a Senior Scientist – Biomarker Development, Translational Medicine, for a Swiss Basel on-site role until 30 April 2027. You will develop and validate soluble biomarker assays (ELISA, MSD, NULISA, Ella) and work at the interface of biology and clinical development.

You will transfer assays to external providers, interpret data for mechanism and dose selection, and ensure rigorous data quality and compliance within a global matrix setting.

Qualifications

• BS/MS degree in Biology, Immunology, or cell biology with 5+ years in pharma/biotech lab work.
• Extensive experience in ligand binding assays (ELISA, MSD, NULISA, Ella) and LC-MS is essential.
• Residency permit or Swiss/EU citizenship required.
• Strong analytical thinking, accountability, and collaborative teamwork.
• Experience in a global, matrix organization is a plus.
• Good computer skills (Excel, Word, PowerPoint, SoftMaxPro, SMART Book, GraphPad Prism, Watson LIMS).
• Good written and oral communication skills.
• Understanding regulatory requirements for Biomarker Development (e.g. GCLP, ICH).

Responsibilities

• Hands-on development and validation of soluble biomarker assays with focus on ligand binding assays (ELISA, MSD, NULISA, Ella, LC-MS).
• Provide SME for transferring, implementing and monitoring assay development at external providers.
• Generate and interpret biomarker data to enable mechanism, dose selection and biology proof in early clinical programs.
• Ensure quality and timely delivery of data from internal and outsourced biomarker activities.
• Lead exploratory soluble biomarker assay strategy, data interpretation, documentation, and alignment to study endpoints.
• Maintain high standards for scientific rigor, documentation, data integrity, compliance, safety, and excellence.

Skills

Biomarker assay development

Ligand binding assays

LC-MS methods

Data interpretation

Cross-functional collaboration

Regulatory understanding

Education

BS/MS in Biology/Immunology/Cell biology

Tools

ELISA

MSD

NULISA

Ella

LC-MS

SoftMaxPro

SMART Book

GraphPad Prism

Watson LIMS

Excel

PowerPoint

Job description

CTC Resourcing Solutions AG is seeking a Senior Scientist – Biomarker Development, Translational Medicine, for a Swiss Basel on-site role until 30 April 2027. You will develop and validate soluble biomarker assays (ELISA, MSD, NULISA, Ella) and work at the interface of biology and clinical development.

You will transfer assays to external providers, interpret data for mechanism and dose selection, and ensure rigorous data quality and compliance within a global matrix setting.