Senior Biomarker Scientist: Translational Assay Development

K-Recruiting GmbH

Schweiz

On-site

CHF 130,000 - 180,000

Full time

6 days ago

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Job summary

Novartis Basel site seeks a Senior Scientist in Biomarker Development to lead soluble biomarker assay development across clinical programs, integrating biology, technology and clinical strategy. You will validate assays like ELISA, MSD, NULISA and LC-MS, while ensuring data integrity and timely delivery across internal and external partners.

The role requires hands-on lab work, cross-functional collaboration, and adherence to GCLP/ICH regulatory standards.

Qualifications

BS/MS degree in Biology, Immunology, Cell biology or equivalent field with experience as a laboratory technician with 5+ year in the pharmaceutical or biotechnology environment.
Extensive understanding, knowledge and practical experience in ligand binding assays are essential, and experience in LC-MS methods and other related technologies will be a plus.
Strong analytical thinking, accountability, and collaborative teamwork.
Experience working in a global organization and matrix-resourcing model is a plus.
Good Computer skills (Excel, Word, PowerPoint, Soft MaxPro, SMART Book, GraphPad Prism, Watson LIMS).
Good written and oral communication skills.
Understanding of regulatory requirement relevant to Biomarker Development (e.g. GCLP, ICH). Based on binding Swiss work permit regulations, this position can only be offered to an applicant that already has an EU/EFTA or Swiss Passport, or a non-EU/EFTA national that already has an unrestricted Swiss Residence & Work Permit or family reunification ”B permit”.

Responsibilities

Hands-on development and validation of soluble biomarker assays with special focus on ligand binding assays such as ELISA, MSD, NULISA, and Ella and other state of the art technologies including LC-MS.
Providing subject matter expertise for transferring, implementation and monitoring of soluble biomarker assay development, validation and sample analysis at external providers.
Generate and interpret biomarker assay data to enable proof of mechanism, dose selection & proof of biology across early clinical programs and present results at internal meetings
Ensuring quality and timely delivery of data generated through internal and outsourced biomarker assay activities.
Serve as the scientific and technical lead for exploratory soluble biomarker assays, including assay strategy, data quality, interpretation, documentation, and alignment to context of use and clinical study endpoints.
Maintain high standards for scientific rigor, documentation, data integrity, compliance, safety, and technical excellence in accordance with applicable Novartis policies and procedures.