Senior Scientist – Biomarker Development, Translational Medicine (7127)

CTC Resourcing Solutions AG; Basel-Stadt; On-site; CHF 110,000 - 150,000; Full time

Job summary

CTC Resourcing Solutions AG is seeking a Senior Scientist – Biomarker Development, Translational Medicine, for a Swiss Basel on-site role until 30 April 2027. You will develop and validate soluble biomarker assays (ELISA, MSD, NULISA, Ella) and work at the interface of biology and clinical development.

You will transfer assays to external providers, interpret data for mechanism and dose selection, and ensure rigorous data quality and compliance within a global matrix setting.

Qualifications

• BS/MS degree in Biology, Immunology, or cell biology with 5+ years in pharma/biotech lab work.
• Extensive experience in ligand binding assays (ELISA, MSD, NULISA, Ella) and LC-MS is essential.
• Residency permit or Swiss/EU citizenship required.
• Strong analytical thinking, accountability, and collaborative teamwork.
• Experience in a global, matrix organization is a plus.
• Good computer skills (Excel, Word, PowerPoint, SoftMaxPro, SMART Book, GraphPad Prism, Watson LIMS).
• Good written and oral communication skills.
• Understanding regulatory requirements for Biomarker Development (e.g. GCLP, ICH).

Responsibilities

• Hands-on development and validation of soluble biomarker assays with focus on ligand binding assays (ELISA, MSD, NULISA, Ella, LC-MS).
• Provide SME for transferring, implementing and monitoring assay development at external providers.
• Generate and interpret biomarker data to enable mechanism, dose selection and biology proof in early clinical programs.
• Ensure quality and timely delivery of data from internal and outsourced biomarker activities.
• Lead exploratory soluble biomarker assay strategy, data interpretation, documentation, and alignment to study endpoints.
• Maintain high standards for scientific rigor, documentation, data integrity, compliance, safety, and excellence.

Skills

Biomarker assay development

Ligand binding assays

LC-MS methods

Data interpretation

Cross-functional collaboration

Regulatory understanding

Education

BS/MS in Biology/Immunology/Cell biology

Tools

ELISA

MSD

NULISA

Ella

LC-MS

SoftMaxPro

SMART Book

GraphPad Prism

Watson LIMS

Excel

PowerPoint

Job description

Senior Scientist – Biomarker Development, Translational Medicine – 7127 ADA

Our client is a pioneer in Drug Discovery and Development and one of the frontrunners in Personalised Healthcare. As the world`s largest R&D spender in the pharmaceutical and diagnostics domain, they work in a vast number of drug discovery & therapeutic areas and are highly recognized internationally.

We are currently looking for a Senior Scientist – Biomarker Development, Translational Medicine for a contract based in Basel, Switzerland until 30th April 2027.

As a Senior Scientist within Molecular & Cellular Sciences (MCS), you will play a critical role in executing exploratory biomarker strategies across our clinical pipeline. You will work at the intersection of biology, technology, and clinical development to deliver innovative biomarker solutions that enable smarter decisions and better outcomes for patients.

This is a hands on laboratory based position where you will develop state of the art biomarker assays across multiple programs, collaborate with global experts, and drive the implementation of cutting-edge biomarker technologies from early development through clinical studies.

This is an on-site job, home office only possible on exceptions.

Main Responsibilities:

• Hands-on development and validation of soluble biomarker assays with special focus on ligand binding assays such as ELISA, MSD, NULISA, and Ella and other state of the art technologies including LC-MS.
• Providing subject matter expertise for transferring, implementation and monitoring of soluble biomarker assay development, validation and sample analysis at external providers.
• Generate and interpret biomarker assay data to enable proof of mechanism, dose selection & proof of biology across early clinical programs and present results at internal meetings
• Ensuring quality and timely delivery of data generated through internal and outsourced biomarker assay activities.
  • Serve as the scientific and technical lead for exploratory soluble biomarker assays, including assay strategy, data quality, interpretation, documentation, and alignment to context of use and clinical study endpoints.
  • Maintain high standards for scientific rigor, documentation, data integrity, compliance, safety, and technical excellence in accordance with applicable policies and procedures.

Qualifications and Experience:

• Relevant working/residency permit or Swiss/EU-Citizenship required
• BS/MS degree in Biology, Immunology, Cell biology or equivalent field with experience as a laboratory technician with 5+ year in the pharmaceutical or biotechnology environment
• Extensive understanding, knowledge and practical experience in ligand binding assays are essential, and experience in LC-MS methods and other related technologies will be a plus.
• Strong analytical thinking, accountability, and collaborative teamwork.
• Experience working in a global organization and matrix-resourcing model is a plus.
• Good Computer skills (Excel, Word, PowerPoint, Soft MaxPro, SMART Book, GraphPad Prism, Watson LIMS).
• Good written and oral communication skills.
• Understanding of regulatory requirement relevant to Biomarker Development (e.g. GCLP, ICH)

Nice to Have:

• Strong track record for providing scientific contributions in biomarkers, translational science, or analytical technologies.
• Established external scientific reputation through conferences, collaborations, publications, or consortia.