Senior Scientist - Biomarker Development

K-Recruiting Life Sciences; Basel; Sur place; CHF 120 000 - 160 000; Plein temps

Résumé du poste

K-Recruiting Life Sciences seeks a Senior Scientist in Basel to execute exploratory biomarker strategies across the clinical pipeline. The role is hands-on, developing state-of-the-art soluble biomarker assays and driving their implementation through early development to clinical studies.

You will lead assay development (ELISA, MSD, NULISA, Ella, LC-MS), collaborate globally, and ensure data quality and timely delivery while adhering to regulatory standards.

Qualifications

• BS/MS in Biology, Immunology, or related field.
• 5+ years in pharma/biotech lab environment.
• Experience with ligand-binding assays (ELISA, MSD, NULISA, Ella).
• LC-MS experience is a plus.
• Strong communication and collaboration skills.
• Understanding of regulatory requirements (GCLP, ICH).

Responsabilités

• Develop and validate soluble biomarker assays (ELISA, MSD, NULISA, Ella).
• Transfer, implement and monitor biomarker assays at external providers.
• Generate and interpret biomarker data for mechanism and biology endpoints.
• Ensure quality and timely data delivery from internal and outsourced activities.
• Lead assay strategy and alignment to study endpoints.
• Maintain scientific rigor, documentation, and compliance.

Connaissances

Biomarker assays

Ligand-binding assays

ELISA

LC-MS

Data interpretation

Teamwork

Regulatory knowledge

Formation

Biology degree

Immunology

Cell biology

Molecular biology

Outils

LC-MS

External labs coordination

Description du poste

Senior Scientist - Biomarker Development (M/F/D)

As a Senior Scientist within Molecular & Cellular Sciences (MCS), you will play a critical role in executing exploratory biomarker strategies across our clinical pipeline. You will work at the intersection of biology, technology, and clinical development to deliver innovative biomarker solutions that enable smarter decisions and better outcomes for patients.

This is a hands on laboratory based position where you will develop state of the art biomarker assays across multiple programs, collaborate with global experts, and drive the implementation of cutting-edge biomarker technologies from early development through clinical studies.

Tasks:

• Hands-on development and validation of soluble biomarker assays with special focus on ligand binding assays such as ELISA, MSD, NULISA, and Ella and other state of the art technologies including LC-MS.
• Providing subject matter expertise for transferring, implementation and monitoring of soluble biomarker assay development, validation and sample analysis at external providers.
• Generate and interpret biomarker assay data to enable proof of mechanism, dose selection & proof of biology across early clinical programs and present results at internal meetings
• Ensuring quality and timely delivery of data generated through internal and outsourced biomarker assay activities.
• Serve as the scientific and technical lead for exploratory soluble biomarker assays, including assay strategy, data quality, interpretation, documentation, and alignment to context of use and clinical study endpoints.
• Maintain high standards for scientific rigor, documentation, data integrity, compliance, safety, and technical excellence in accordance with applicable policies and procedures.

Qualification:

• BS/MS degree in Biology, Immunology, Cell biology or equivalent field with experience as a laboratory technician with 5+ year in the pharmaceutical or biotechnology environment
• Extensive understanding, knowledge and practical experience in ligand binding assays are essential, and experience in LC-MS methods and other related technologies will be a plus.
• Strong analytical thinking, accountability, and collaborative teamwork.
• Experience working in a global organization and matrix-resourcing model is a plus.
• Good written and oral communication skills.
• Understanding of regulatory requirement relevant to Biomarker Development (e.g. GCLP, ICH) Based on binding Swiss work permit regulations, this position can only be offered to an applicant that already has an EU/EFTA or Swiss Passport, or a non-EU/EFTA national that already has an unrestricted Swiss Residence & Work Permit or family reunification B permit.
• Preferred Qualifications
• Strong track record for providing scientific contributions in biomarkers, translational science, or analytical technologies.
• Established external scientific reputation through conferences, collaborations, publications, or consortia.