Scale-Up Process Scientist: Lab to Production

Placements24; LegKraal Gate; On-site; ZAR 900,000 - 1,300,000; Full time

Benefits offered by this job

Competitive salary

Career development opportunities

Exposure to diverse R&D projects

Collaborative work environment

State-of-the-art facilities

Job summary

Placements24 is seeking an experienced Senior Process Development Scientist to join our client’s R&D team in Mahikeng. You will develop and optimize manufacturing processes for novel chemical entities and pharmaceutical products, translating lab-scale methods into robust, cost-effective production routes.

You will work closely with chemists, engineers, and manufacturing personnel to transfer technology while ensuring quality and regulatory standards.

Qualifications

• PhD or MSc in Chemistry, Chemical Engineering, or a related field.
• 5+ years of experience in process chemistry or process development within the pharmaceutical or fine chemical industry.
• Strong understanding of organic synthesis, reaction kinetics, thermodynamics, and chemical engineering principles.
• Experience with process scale-up, technology transfer, and manufacturing operations.
• Proficiency in analytical techniques for process monitoring and product characterization.
• Excellent problem-solving, project management, and communication skills.

Responsibilities

• Develop and optimize chemical synthesis and purification processes for target molecules, focusing on yield, purity, and efficiency.
• Conduct process safety assessments and identify potential hazards, implementing mitigation strategies.
• Lead scale-up activities from laboratory bench to pilot plant and commercial manufacturing scales.
• Utilize Design of Experiments (DoE) and other statistical tools to optimize process parameters and understand critical process variables.
• Troubleshoot process issues and implement corrective actions to ensure consistent product quality and yield.
• Author process development reports, technology transfer documents, and contribute to regulatory filings.

Skills

Problem-solving

Project management

Communication skills

Process scale-up

DoE (Design of Experiments)

Education

PhD in Chemistry or Chemical Engineering

Master's in Chemistry or Chemical Engineering

Tools

Analytical techniques

Job description

Placements24 is seeking an experienced Senior Process Development Scientist to join our client’s R&D team in Mahikeng. You will develop and optimize manufacturing processes for novel chemical entities and pharmaceutical products, translating lab-scale methods into robust, cost-effective production routes.

You will work closely with chemists, engineers, and manufacturing personnel to transfer technology while ensuring quality and regulatory standards.