Senior Process Development Scientist: Scale-Up & Innovation

Placements24; Sandton; On-site; ZAR 1,000,000 - 1,700,000; Full time

Benefits offered by this job

Competitive salary with incentives

Health, dental, retirement benefits

State-of-the-art labs and pilot plant

Job summary

Placements24 seeks a Senior Process Development Scientist to join our R&D team in Sandton. You will design, optimize, and scale up manufacturing processes for novel chemical entities and biologics, translating lab-scale discoveries into robust, scalable operations.

The role requires expertise in chemical engineering, reaction kinetics, and technology transfer, with hands-on experience in PAT/QbD concepts. A PhD/MSc and 6+ years in pharma/chem/biotech process development are preferred.

Qualifications

• MSc or PhD in Chemical Engineering, Chemistry, or related field.
• 6+ years of process development experience in pharma/biotech/chemical industries.
• Strong knowledge of reaction kinetics, thermodynamics, and unit operations.
• Experience with scale-up, technology transfer, and process validation.
• Familiarity with PAT and QbD is desirable.

Responsibilities

• Design and execute experiments to optimize reaction conditions, yields, and purity for manufacturing processes.
• Develop and validate scalable processes, considering safety, environmental impact, and cost‑effectiveness.
• Troubleshoot process‑related issues during development and scale‑up phases.
• Perform process characterization and risk assessments to ensure process robustness and control.
• Collaborate with engineering and manufacturing teams to ensure successful technology transfer and implementation.
• Author comprehensive process development reports, documentation, and regulatory submissions.

Skills

Process development

Scale-up

Project management

Analytical skills

Education

MSc or PhD in Chemical Engineering, Chemistry, or related field

Tools

PAT

QbD

Job description

Placements24 seeks a Senior Process Development Scientist to join our R&D team in Sandton. You will design, optimize, and scale up manufacturing processes for novel chemical entities and biologics, translating lab-scale discoveries into robust, scalable operations.

The role requires expertise in chemical engineering, reaction kinetics, and technology transfer, with hands-on experience in PAT/QbD concepts. A PhD/MSc and 6+ years in pharma/chem/biotech process development are preferred.