Upstream Bioprocess Scientist — Scale-Up & Tech Transfer Lead

Pfizer; Bothell (WA); On-site; USD 69,000 - 114,000; Full time

Benefits offered by this job

401(k) with company match

Retirement savings contribution

Paid vacation

Paid holidays

Parental leave

Medical, dental, and vision benefits

Job summary

Pfizer is seeking a Senior Associate Scientist (R2) in Upstream Process Development to design, optimize and scale recombinant protein manufacturing processes for early- and late-phase trials. You will lead bench-scale experiments, transfer technology to GMP facilities, and contribute to regulatory submissions.

The role involves documenting results, collaborating across teams, and supporting process development through scale-up and technology maturation.

Qualifications

• Bachelor’s degree with 3 years’ industrial experience or Master’s degree with 0-2 years experience in Chemical / Biochemical Engineering, Cell Biology, Biotechnology, Biomedical Engineering or a relevant field.
• Relevant research experience in a laboratory setting is required.
• Ability to grasp scientific concepts, interpret complex data, and formulate new hypothesis.
• Competency in aseptic laboratory technique and the ability to design and carry out complex experiments and interpret data.
• Demonstrated effectiveness in collaborative projects, and ability to communicate effectively with scientists and management in a highly matrixed organization.

Responsibilities

• Design and execute experiments in appropriate scale-down models such as shake flasks and bioreactors to develop robust, high yield, scalable manufacturing processes.
• Serve as upstream technical lead; ensure accurate technology transfer to pilot and GMP manufacturing facilities; provide technical support during manufacturing campaigns as needed.
• Timely and accurately document data in electronic lab notebooks; author technical reports and contribute to regulatory submissions such as IND and BLA.
• Participate in lab and project team meetings on design of experiments and data interpretation.
• Contribute to a safe, efficient lab environment and be a collaborative team player.
• Occasionally work over the weekend to passage flasks, sample bioreactors or perform other essential tasks.

Skills

Aseptic technique

Data interpretation

Experimental design

Collaborative work

Scientific communication

Education

Bachelor’s degree in Chemical/Biochemical Engineering or related field

Master’s degree in a relevant field

Tools

ambr15

ambr250

Shake flasks

Bioreactors

Job description

Pfizer is seeking a Senior Associate Scientist (R2) in Upstream Process Development to design, optimize and scale recombinant protein manufacturing processes for early- and late-phase trials. You will lead bench-scale experiments, transfer technology to GMP facilities, and contribute to regulatory submissions.

The role involves documenting results, collaborating across teams, and supporting process development through scale-up and technology maturation.