Translational Data Science Lead – Single-Cell & MRD Insights

AstraZeneca; Waltham (MA); Hybrid; USD 138,000 - 208,000; Full time

Benefits offered by this job

Incentives

Equity-based awards

Retirement programs

Health, dental, and vision

Job summary

AstraZeneca in Cambridge, MA is seeking a senior data scientist to translate multimodal clinical and molecular data into decisions that drive hematology programs. You will lead translational data initiatives, apply AI and statistical learning to single-cell and multiomics data, and build interfaces that deliver rapid, reliable insights for study design.

You will mentor junior data scientists, partner with biomarker science, biostatistics, and data engineering to embed analytics into program

Qualifications

• Advanced degree with 5+ years in translational data analytics or related field.
• Proven expertise applying AI/ML to high‑dimensional biological data (MRD, single‑cell).
• Strong programming in R and Python; experience with scalable analytics workflows.

Responsibilities

• Lead translational data initiatives across hematology programs.
• Build interfaces and dashboards for rapid insight delivery to scientists and clinicians.
• Develop reproducible analytics pipelines from QC to reporting; mentor teammates.

Skills

AI/ML in bio data

Single-cell analysis

MRD biomarkers

Python

R

Data visualization dashboards

Education

Masters Degree

Tools

Shiny

Dash

Nextflow

Docker

AWS

Job description

AstraZeneca in Cambridge, MA is seeking a senior data scientist to translate multimodal clinical and molecular data into decisions that drive hematology programs. You will lead translational data initiatives, apply AI and statistical learning to single-cell and multiomics data, and build interfaces that deliver rapid, reliable insights for study design.

You will mentor junior data scientists, partner with biomarker science, biostatistics, and data engineering to embed analytics into program