Director, Hematology AI & RWE Strategy

AstraZeneca GmbH; Boston (MA); On-site; USD 156,000 - 233,000; Full time

Benefits offered by this job

In-office role in Boston

Base pay with incentives

Health, dental, vision benefits

Retirement Benefits

Job summary

AstraZeneca GmbH is seeking a Director of Hematology Clinical Intelligence & Real-World Evidence Strategy in Boston. You will lead end-to-end evidence generation aligning with R&D, regulatory filings, and market access, translating complex data into actionable portfolio decisions.

The role requires deep expertise in multimodal data and collaboration across Translational Science, Clinical Development, and Market Access to shape AI-enabled evidence platforms.

Qualifications

• Advanced degree in a quantitative field with health outcomes/epidemiology focus.
• Experience translating analytical outputs into strategic portfolio recommendations.
• Proven ability to lead without authority and influence senior stakeholders in a matrixed environment.

Responsibilities

• Own the Hematology clinical intelligence and real-world evidence strategy end to end from R&D to patient care.
• Define and prioritize evidence gaps the matter most for PH3ID, external control arms, and subpopulation discovery.
• Partner with Translational Science and Clinical Development to bring multimodal signals (genomics, imaging, digital endpoints) into development strategies.
• Advance AI-enabled approaches in Hematology, including tumor dynamics forecasting and trial simulation.
• Turn internal and competitor trial data and real-world data into insights on care pathways and competitive positioning.
• Influence Global Product Teams and external data partners to keep outputs rigorous and relevant.
• Build Hematology-specific intelligence that persists across use cases within PH3ID Foundation.

Skills

Evidence generation

RWE

Multimodal modeling

AI-enabled evidence

Portfolio strategy

Stakeholder management

Education

PhD/MD/PharmD or equivalent in epidemiology/biostatistics/health economics

5+ years in evidence generation/RWE/HEOR

Job description

AstraZeneca GmbH is seeking a Director of Hematology Clinical Intelligence & Real-World Evidence Strategy in Boston. You will lead end-to-end evidence generation aligning with R&D, regulatory filings, and market access, translating complex data into actionable portfolio decisions.

The role requires deep expertise in multimodal data and collaboration across Translational Science, Clinical Development, and Market Access to shape AI-enabled evidence platforms.