Lead Translational Biomarker Scientist, Oncology/Hematology

Merck

Boston (MA)

On-site

USD 191,000 - 300,000

Full time

13 days ago
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Job summary

Merck seeks a Principal Scientist to provide strategic biomarker leadership across Oncology and Hematology programs. You will design and execute translational biomarker strategies spanning early to late development, integrating biology, pharmacodynamics, and clinical endpoints to inform program decisions.

Key responsibilities include leading cross-functional biomarker input, communicating results to governance groups, and mentoring team members to build a rigorous translational biomarker

Qualifications

  • Significant experience developing and executing translational or clinical biomarker strategies in oncology or hematology drug development.
  • Strong scientific expertise in cancer biology and translational oncology.
  • Ability to translate hypotheses into biomarker strategies that inform clinical decisions.

Responsibilities

  • Develop and lead integrated biomarker strategies across oncology and hematology programs with cross-functional teams.
  • Translate biology into hypotheses and fit-for-purpose biomarker approaches.
  • Define biomarker questions for biology proof, target engagement, dose decisions, and patient selection.
  • Lead interpretation of biomarker and clinical data and provide actionable recommendations.
  • Mentor biomarker scientists and contribute to a collaborative biomarker organization.

Skills

Biomarkers
Clinical Development
Clinical Research
Ethical Compliance
Immuno-Oncology
Mechanism of Action
Oncology
Patient Care
Pharmacodynamics
Protocol Development
Research Designs
Scientific Presentations
Scientific Writing
Strategic Thinking
Translational Medicine

Education

Ph.D., M.D. or equivalent

Job description

Merck seeks a Principal Scientist to provide strategic biomarker leadership across Oncology and Hematology programs. You will design and execute translational biomarker strategies spanning early to late development, integrating biology, pharmacodynamics, and clinical endpoints to inform program decisions.

Key responsibilities include leading cross-functional biomarker input, communicating results to governance groups, and mentoring team members to build a rigorous translational biomarker

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