Senior Translational Pharmacology Lead, CVRM

Genentech; South San Francisco (CA); On-site; USD 116,000 - 215,000; Full time

Benefits offered by this job

Relocation assistance

Job summary

Genentech in South San Francisco, CA is seeking a highly motivated scientist to lead pharmacology efforts within the CVRM Translational Biology group. The role focuses on driving drug discovery and mechanistic studies, coordinating multidisciplinary teams to advance candidates toward clinical development.

The ideal candidate has a PhD and 3+ years of post‑graduate experience with cardio‑metabolic diseases and strong in‑vivo expertise, including cardiovascular models and phenotyping.

Qualifications

• PhD in Pharmacology, Biology or other related field with 3+ years relevant post‑graduate experience.
• Knowledge in the cardio‑metabolic disease field with a strong in‑vivo background.
• Hands‑on experience with cardiovascular models (e.g., ischemia reperfusion injury, TAC) and phenotyping (echocardiography, catheterization).
• A scientist with passion for hands‑on research and desire to lead from the bench.
• Ability to multitask and contribute to several projects while remaining well organized.
• Ability to take unique and creative approaches to solve challenging problems.
• Good interpersonal skills and ability to work well with a multidisciplinary team and effectively communicate in cross‑functional forums.

Responsibilities

• Provide scientific and technical hands-on support for research involving in vivo and ex vivo studies in animal models with the goal of progressing drug candidates into clinical development and beyond.
• Plan and execute experiments, develop protocols, document data, troubleshoot problems, interpret data and communicate results.
• Advise on technical or project strategy as appropriate.
• Mentor and train junior members to be scientifically and technically proficient.
• Manage studies performed at CROs, evaluate data, develop technical documents and assist with regulatory submission materials.
• Work collaboratively within multidisciplinary project teams.
• Effectively communicate lab activities, timelines and results to team members and collaborators.

Skills

Multitasking

Cross-functional collaboration

Scientific communication

Mentoring

Education

PhD in Pharmacology or related field

Job description

Genentech in South San Francisco, CA is seeking a highly motivated scientist to lead pharmacology efforts within the CVRM Translational Biology group. The role focuses on driving drug discovery and mechanistic studies, coordinating multidisciplinary teams to advance candidates toward clinical development.

The ideal candidate has a PhD and 3+ years of post‑graduate experience with cardio‑metabolic diseases and strong in‑vivo expertise, including cardiovascular models and phenotyping.