Director, Clinical Development/Science

EPM Scientific; California; Remote; USD 180,000 - 240,000; Full time

Job summary

EPM Scientific is seeking a Director of Clinical Development/Science to lead clinical strategy for CVRM programs. This remote role requires base in PST US, reporting to the CMO and EVP Translational Research, and collaboration across R&D, regulatory and external partners.

You will design protocols, oversee study execution, medical monitoring, site engagement, and ensure data integrity and patient safety in early-stage trials.

Qualifications

• MD or PhD with 5+ years in clinical development.
• Experience in cardio, metabolic or related disease areas.
• Ability to lead clinical science strategy in early-stage trials.
• Gene therapy experience preferred.
• Strong analytical and decision-making skills.
• Excellent communication and teamwork across functions.
• Cross-cultural collaboration across geographies (US, China, Australia).

Responsibilities

• Serve as clinical science lead for clinical stage CVRM programs.
• Support day-to-day study execution with protocol, timelines, and regulatory requirements.
• Participate in medical monitoring: review data with cross-functional colleagues to ensure data quality and safety; escalate issues as appropriate.
• Participate in site selection, initiation and ongoing engagement; provide scientific support to investigators.
• Design and develop clinical trial protocols and associated documents in collaboration with CMO.
• Collaborate with clinical and non-clinical teams to ensure alignment.

Skills

Clinical leadership

Cross-functional collab

Data interpretation

Regulatory knowledge

Communication skills

Problem solving

Team player

Education

MD/PhD

Job description

Job Title: Director, Clinical Development/Science

Department: Clinical Development

Reports To: Chief Medical Officer, Executive Vice President of Translational Research

Location: Remote (US) --- Must be based in PST

Employment Type: Full-Time

Key Responsibilities

• Serve as clinical science lead and core member of clinical development team for clinical stage CVRM programs
• Support day-to-day study execution, ensuring alignment with protocol, timelines, and regulatory requirements
• Participate in medical monitoring activities: review and interpret clinical data on an ongoing basis in collaboration with cross-functional colleagues and external partners to ensure data quality, participant safety, and protocol compliance. Escalate issues as appropriate.
• Participate in site selection, initiation, and ongoing engagement; provide scientific support to investigators and address protocol-related inquiries
• Design and develop clinical trial protocols and associated documents (e.g. clinical study plans, data review plans, case report forms (CRFs), database design, statistical analysis plans) in collaboration with CMO
• Collaborate with clinical & non-clinical teams to ensure alignment

Qualifications

Education & Experience

• MD or PhD; and 5+ years of industry experience in clinical development.
• Experience with cardio, metabolic or related disease areas required.
• Demonstrated ability to lead clinical science strategy and execution in early-stage trials
• Gene therapy experience preferred.
• Strong critical thinking and problem-solving skills.
• Good team player, excellent communication skills, learning agility.
• Cross-Cultural Agility: Proven ability to collaborate across geographies (U.S., China, Australia) and functions (R&D, BD, regulatory) in matrixed environments.
• Strong analytical and decision-making skills to translate scientific insights into actionable clinical strategies.

Location & Logistics

• Primary Base: US (Remote)
• Flexibility: Willingness to adapt to dynamic priorities in a high-growth biotech setting.