Senior Translational Safety Pathologist

Genentech; San Francisco (CA); On-site; USD 199,000 - 369,000; Full time

Job summary

Genentech, based in South San Francisco, seeks a Senior Principal Pathologist-Scientist to provide independent pathology leadership across early discovery through clinical development. You will integrate pathology, toxicology, pharmacology, and translational data to shape safety strategies and enable timely decisions.

The role combines hands-on evaluation with strategic influence, mentoring colleagues, and representing Translational Safety in interactions with health authorities.

Qualifications

• FDA/industry drug-development experience with translational safety.
• 5+ years in nonclinical safety/pathology within pharma/biotech.
• Ability to work cross-functionally and influence senior teams.

Responsibilities

• Lead pathology strategy for multiple development programs.
• Provide expert input on necropsy, clinical pathology, and histopathology.
• Collaborate with toxicologists, pharmacologists, clinicians, and regulators.
• Synthesize complex data to guide dose selection and program decisions.
• Lead and mentor scientists; contribute to publications and scientific forums.

Skills

Cross-functional leadership

Strategic decision making

Regulatory communication

Education

DVM/VMD degree

ACVP/ECVP board certification

PhD or equivalent

Tools

NAMs

Digital pathology

Computational pathology

Job description

Genentech, based in South San Francisco, seeks a Senior Principal Pathologist-Scientist to provide independent pathology leadership across early discovery through clinical development. You will integrate pathology, toxicology, pharmacology, and translational data to shape safety strategies and enable timely decisions.

The role combines hands-on evaluation with strategic influence, mentoring colleagues, and representing Translational Safety in interactions with health authorities.