Senior Scientist, Gene Delivery & Formulation

Praxy; Seattle, Northern (WA, KY); Hybrid; USD 124,000 - 150,000; Full time

Job summary

Bristol Myers Squibb is seeking a Senior Scientist to lead formulation and drug product development for LVV, AAV, mRNA, and LNP systems. The role emphasizes biophysical stability, freeze/thaw processes, lyophilization, and thermostabilization to reduce cold-chain burden.

The incumbent will design stability studies, develop robust excipient systems, and support tech transfer, scale-up, and regulatory documentation while collaborating with process development, analytics, and manufacturing teams.

Qualifications

• Ph.D. in a relevant field or a combination of MS/BS with extensive formulation/drug product experience.
• Experience with biophysical characterization and stability of biologics or advanced modalities.

Responsibilities

• Design and execute stability-enabling formulation studies for LVV, AAV, mRNA, and LNP products.
• Lead freeze/thaw and lyophilization cycle development with attention to Tg′ and collapse behavior.
• Communicate data and progress to cross-functional teams and external partners.

Skills

Biophysical stability

Freeze/thaw stability

DLS

Lyophilization

Buffer design

Regulatory awareness

Clear communication

Education

PhD in Pharmaceutical Sciences or related field

Tools

DSC/mDSC

Freeze-drying microscopy

DLS

NTA

MFI

Job description

Bristol Myers Squibb is seeking a Senior Scientist to lead formulation and drug product development for LVV, AAV, mRNA, and LNP systems. The role emphasizes biophysical stability, freeze/thaw processes, lyophilization, and thermostabilization to reduce cold-chain burden.

The incumbent will design stability studies, develop robust excipient systems, and support tech transfer, scale-up, and regulatory documentation while collaborating with process development, analytics, and manufacturing teams.